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STRINGSTRING
ZNF410 ZNF410 TNKS TNKS UBC UBC CKS2 CKS2 RNF146 RNF146 BLZF1 BLZF1 ACBD3 ACBD3 RAB2A RAB2A GORASP1 GORASP1 GORASP2 GORASP2 FKTN FKTN
"BLZF1" - basic leucine zipper nuclear factor 1 in Homo sapiens
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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BLZF1basic leucine zipper nuclear factor 1; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface (400 aa)    
Predicted Functional Partners:
GORASP2
golgi reassembly stacking protein 2, 55kDa; Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA (452 aa)
        score_image score_image score_image   0.999
RAB2A
RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex (212 aa)
        score_image score_image score_image   0.998
CKS2
CDC28 protein kinase regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function (79 aa)
        score_image   score_image   0.689
RNF146
ring finger protein 146; E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated (PARsylated) proteins and mediates their ubiquitination and subsequent degradation. May regulate many important biological processes, such as cell survival and DNA damage response. Acts as an activator of the Wnt signaling pathway by mediating the ubiquitination of PARsylated AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex. Acts in cooperation with tankyrase proteins (TNKS and TNKS2), which mediate PARsylation of target proteins AXIN1, AXIN2, BLZF1, CASC3, TNKS an [...] (359 aa)
        score_image   score_image   0.656
GORASP1
golgi reassembly stacking protein 1, 65kDa; Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity- its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes (440 aa)
            score_image   0.627
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex- poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequ [...] (1327 aa)
        score_image       0.566
FKTN
fukutin; May be a glycosyltransferase which participates in glycosylation of alpha-dystroglycan/DAG1. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development (461 aa)
            score_image   0.493
ZNF410
zinc finger protein 410; Transcription factor that activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence (516 aa)
        score_image       0.485
ACBD3
acyl-CoA binding domain containing 3; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity) (528 aa)
        score_image   score_image   0.483
UBC
ubiquitin C (685 aa)
        score_image       0.483
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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