node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATAT1 | BBIP1 | ENSP00000327832 | ENSP00000433157 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | BBSome interacting protein 1; Required for primary cilia assembly and BBSome stability. Regulates cytoplasmic microtubule stability and acetylation | 0.471 |
ATAT1 | FHDC1 | ENSP00000327832 | ENSP00000260008 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | FH2 domain containing 1 | 0.708 |
ATAT1 | FHOD1 | ENSP00000327832 | ENSP00000258201 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | formin homology 2 domain containing 1; Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing | 0.629 |
ATAT1 | HDAC6 | ENSP00000327832 | ENSP00000334061 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin | 0.657 |
ATAT1 | NAA50 | ENSP00000327832 | ENSP00000240922 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | N(alpha)-acetyltransferase 50, NatE catalytic subunit; Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity | 0.541 |
ATAT1 | PHEX | ENSP00000327832 | ENSP00000368682 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | phosphate regulating endopeptidase homolog, X-linked; Probably involved in bone and dentin mineralization and renal phosphate reabsorption | 0.514 |
ATAT1 | TMEM27 | ENSP00000327832 | ENSP00000369699 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | transmembrane protein 27; Regulator of SNARE complex function. Stimulator of beta cell replication | 0.495 |
ATAT1 | TPPP2 | ENSP00000327832 | ENSP00000317595 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | tubulin polymerization-promoting protein family member 2; May bind tubulin but has no microtubule bundling activity | 0.763 |
ATAT1 | TUBB1 | ENSP00000327832 | ENSP00000217133 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | tubulin, beta 1 class VI; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) | 0.483 |
ATAT1 | TUBB6 | ENSP00000327832 | ENSP00000318697 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | tubulin, beta 6 class V; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) | 0.527 |
BBIP1 | ATAT1 | ENSP00000433157 | ENSP00000327832 | BBSome interacting protein 1; Required for primary cilia assembly and BBSome stability. Regulates cytoplasmic microtubule stability and acetylation | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | 0.471 |
FHDC1 | ATAT1 | ENSP00000260008 | ENSP00000327832 | FH2 domain containing 1 | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | 0.708 |
FHDC1 | FHOD1 | ENSP00000260008 | ENSP00000258201 | FH2 domain containing 1 | formin homology 2 domain containing 1; Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing | 0.765 |
FHOD1 | ATAT1 | ENSP00000258201 | ENSP00000327832 | formin homology 2 domain containing 1; Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | 0.629 |
FHOD1 | FHDC1 | ENSP00000258201 | ENSP00000260008 | formin homology 2 domain containing 1; Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing | FH2 domain containing 1 | 0.765 |
HDAC6 | ATAT1 | ENSP00000334061 | ENSP00000327832 | histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | 0.657 |
HDAC6 | TUBB1 | ENSP00000334061 | ENSP00000217133 | histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin | tubulin, beta 1 class VI; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) | 0.410 |
HDAC6 | TUBB6 | ENSP00000334061 | ENSP00000318697 | histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin | tubulin, beta 6 class V; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) | 0.561 |
NAA50 | ATAT1 | ENSP00000240922 | ENSP00000327832 | N(alpha)-acetyltransferase 50, NatE catalytic subunit; Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | 0.541 |
PHEX | ATAT1 | ENSP00000368682 | ENSP00000327832 | phosphate regulating endopeptidase homolog, X-linked; Probably involved in bone and dentin mineralization and renal phosphate reabsorption | alpha tubulin acetyltransferase 1; Specifically acetylates ’Lys-40’ in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development (By similarity) | 0.514 |