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STRINGSTRING
WDR61 WDR61 CWF19L2 CWF19L2 WDR53 WDR53 FAM86B1 FAM86B1 ZDHHC9 ZDHHC9 TM4SF19 TM4SF19 OR4K1 OR4K1 POTEB POTEB FAM86B2 FAM86B2 OR4K2 OR4K2 OR4N2 OR4N2
"WDR53" - WD repeat domain 53 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR53WD repeat domain 53 (358 aa)    
Predicted Functional Partners:
TM4SF19
transmembrane 4 L six family member 19 (209 aa)
            score_image   0.754
CWF19L2
CWF19-like 2, cell cycle control (S. pombe) (894 aa)
            score_image   0.585
OR4K2
olfactory receptor, family 4, subfamily K, member 2; Odorant receptor (Potential) (314 aa)
            score_image   0.532
FAM86B2
family with sequence similarity 86, member B2 (330 aa)
            score_image   0.503
FAM86B1
family with sequence similarity 86, member B1 (330 aa)
            score_image   0.502
ZDHHC9
zinc finger, DHHC-type containing 9 (364 aa)
            score_image   0.499
OR4N2
olfactory receptor, family 4, subfamily N, member 2; Odorant receptor (Potential) (307 aa)
            score_image   0.499
OR4K1
olfactory receptor, family 4, subfamily K, member 1; Odorant receptor (Potential) (311 aa)
            score_image   0.472
WDR61
WD repeat domain 61; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non- phosphorylated and ’Ser-2’- and ’Ser-5’-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target gene [...] (305 aa)
    score_image           0.430
POTEB
POTE ankyrin domain family, member B (544 aa)
            score_image   0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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