MINA protein (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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Score

MINA

MYC induced nuclear antigen (465 aa)

Predicted Functional Partners:

MYC

0.992

MAX

0.900

UBC

0.799

LRP4

0.752

WNT7A

0.681

NAA16

0.671

TXNL1

0.644

SP8

0.644

SP7

0.636

MYBBP1A

0.625

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LRP4	MINA	ENSP00000367888	ENSP00000328251	low density lipoprotein receptor-related protein 4; Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN- induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the [...]	MYC induced nuclear antigen	0.752
LRP4	WNT7A	ENSP00000367888	ENSP00000285018	low density lipoprotein receptor-related protein 4; Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN- induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the [...]	wingless-type MMTV integration site family, member 7A; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity)	0.636
MAX	MINA	ENSP00000351490	ENSP00000328251	MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity	MYC induced nuclear antigen	0.900
MAX	MYC	ENSP00000351490	ENSP00000367207	MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity	v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes	0.999
MINA	LRP4	ENSP00000328251	ENSP00000367888	MYC induced nuclear antigen	low density lipoprotein receptor-related protein 4; Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN- induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the [...]	0.752
MINA	MAX	ENSP00000328251	ENSP00000351490	MYC induced nuclear antigen	MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity	0.900
MINA	MYBBP1A	ENSP00000328251	ENSP00000370968	MYC induced nuclear antigen	MYB binding protein (P160) 1a; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity)	0.625
MINA	MYC	ENSP00000328251	ENSP00000367207	MYC induced nuclear antigen	v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes	0.992
MINA	NAA16	ENSP00000328251	ENSP00000368716	MYC induced nuclear antigen	N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity)	0.671
MINA	SP7	ENSP00000328251	ENSP00000302812	MYC induced nuclear antigen	Sp7 transcription factor; Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity)	0.636
MINA	SP8	ENSP00000328251	ENSP00000408792	MYC induced nuclear antigen	Sp8 transcription factor; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity)	0.644
MINA	TXNL1	ENSP00000328251	ENSP00000217515	MYC induced nuclear antigen	thioredoxin-like 1; Active thioredoxin with a redox potential of about -250 mV	0.644
MINA	UBC	ENSP00000328251	ENSP00000344818	MYC induced nuclear antigen	ubiquitin C	0.799
MINA	WNT7A	ENSP00000328251	ENSP00000285018	MYC induced nuclear antigen	wingless-type MMTV integration site family, member 7A; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts (By similarity)	0.681
MYBBP1A	MINA	ENSP00000370968	ENSP00000328251	MYB binding protein (P160) 1a; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity)	MYC induced nuclear antigen	0.625
MYBBP1A	UBC	ENSP00000370968	ENSP00000344818	MYB binding protein (P160) 1a; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity)	ubiquitin C	0.958
MYC	MAX	ENSP00000367207	ENSP00000351490	v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes	MYC associated factor X; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5’-CAC[GA]TG-3’. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 ’Lys-9’ histone methyltransferase activity	0.999
MYC	MINA	ENSP00000367207	ENSP00000328251	v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes	MYC induced nuclear antigen	0.992
MYC	UBC	ENSP00000367207	ENSP00000344818	v-myc myelocytomatosis viral oncogene homolog (avian); Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5’-CAC[GA]TG-3’. Seems to activate the transcription of growth-related genes	ubiquitin C	0.999
NAA16	MINA	ENSP00000368716	ENSP00000328251	N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity)	MYC induced nuclear antigen	0.671

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