FAM110C protein (Homo sapiens) - STRING network view

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FAM110C

family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway (321 aa)

Predicted Functional Partners:

FAM110A

0.889

CSPP1

0.888

CSNK1E

0.618

AKT1

0.576

C6orf1

0.416

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	FAM110C	ENSP00000270202	ENSP00000328347	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	0.576
C6orf1	FAM110C	ENSP00000378441	ENSP00000328347	chromosome 6 open reading frame 1	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	0.416
CSNK1E	FAM110C	ENSP00000352929	ENSP00000328347	casein kinase 1, epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	0.618
CSPP1	FAM110A	ENSP00000262210	ENSP00000246100	centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization	family with sequence similarity 110, member A	0.889
CSPP1	FAM110C	ENSP00000262210	ENSP00000328347	centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	0.888
FAM110A	CSPP1	ENSP00000246100	ENSP00000262210	family with sequence similarity 110, member A	centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization	0.889
FAM110A	FAM110C	ENSP00000246100	ENSP00000328347	family with sequence similarity 110, member A	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	0.889
FAM110C	AKT1	ENSP00000328347	ENSP00000270202	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	v-akt murine thymoma viral oncogene homolog 1; AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation o [...]	0.576
FAM110C	C6orf1	ENSP00000328347	ENSP00000378441	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	chromosome 6 open reading frame 1	0.416
FAM110C	CSNK1E	ENSP00000328347	ENSP00000352929	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	casein kinase 1, epsilon; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation	0.618
FAM110C	CSPP1	ENSP00000328347	ENSP00000262210	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	centrosome and spindle pole associated protein 1; May play a role in cell-cycle-dependent microtubule organization	0.888
FAM110C	FAM110A	ENSP00000328347	ENSP00000246100	family with sequence similarity 110, member C; May play a role in microtubule organization. May play a role in cell spreading and cell migration of epithelial cells; the function may involve the AKT1 signaling pathway	family with sequence similarity 110, member A	0.889

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