node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNR1 | CXCL12 | ENSP00000358511 | ENSP00000379140 | cannabinoid receptor 1 (brain) | chemokine (C-X-C motif) ligand 12 | 0.921 |
CNR1 | CXCL13 | ENSP00000358511 | ENSP00000286758 | cannabinoid receptor 1 (brain) | chemokine (C-X-C motif) ligand 13; Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5 | 0.907 |
CNR1 | CXCR3 | ENSP00000358511 | ENSP00000362795 | cannabinoid receptor 1 (brain) | chemokine (C-X-C motif) receptor 3; Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC) | 0.908 |
CNR1 | GNA12 | ENSP00000358511 | ENSP00000275364 | cannabinoid receptor 1 (brain) | guanine nucleotide binding protein (G protein) alpha 12; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems | 0.460 |
CNR1 | GNAI1 | ENSP00000358511 | ENSP00000343027 | cannabinoid receptor 1 (brain) | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.956 |
CNR1 | GNAO1 | ENSP00000358511 | ENSP00000262493 | cannabinoid receptor 1 (brain) | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14 | 0.831 |
CNR1 | LPAR3 | ENSP00000358511 | ENSP00000359643 | cannabinoid receptor 1 (brain) | lysophosphatidic acid receptor 3; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins | 0.904 |
CNR1 | LPAR5 | ENSP00000358511 | ENSP00000327875 | cannabinoid receptor 1 (brain) | lysophosphatidic acid receptor 5; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities | 0.900 |
CNR1 | S1PR4 | ENSP00000358511 | ENSP00000246115 | cannabinoid receptor 1 (brain) | sphingosine-1-phosphate receptor 4; Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes | 0.900 |
CNR1 | S1PR5 | ENSP00000358511 | ENSP00000328472 | cannabinoid receptor 1 (brain) | sphingosine-1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells | 0.913 |
CXCL12 | CNR1 | ENSP00000379140 | ENSP00000358511 | chemokine (C-X-C motif) ligand 12 | cannabinoid receptor 1 (brain) | 0.921 |
CXCL12 | CXCL13 | ENSP00000379140 | ENSP00000286758 | chemokine (C-X-C motif) ligand 12 | chemokine (C-X-C motif) ligand 13; Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5 | 0.963 |
CXCL12 | CXCR3 | ENSP00000379140 | ENSP00000362795 | chemokine (C-X-C motif) ligand 12 | chemokine (C-X-C motif) receptor 3; Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC) | 0.981 |
CXCL12 | GNAI1 | ENSP00000379140 | ENSP00000343027 | chemokine (C-X-C motif) ligand 12 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.900 |
CXCL12 | GNAO1 | ENSP00000379140 | ENSP00000262493 | chemokine (C-X-C motif) ligand 12 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14 | 0.912 |
CXCL12 | LPAR3 | ENSP00000379140 | ENSP00000359643 | chemokine (C-X-C motif) ligand 12 | lysophosphatidic acid receptor 3; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins | 0.981 |
CXCL12 | LPAR5 | ENSP00000379140 | ENSP00000327875 | chemokine (C-X-C motif) ligand 12 | lysophosphatidic acid receptor 5; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities | 0.900 |
CXCL12 | S1PR4 | ENSP00000379140 | ENSP00000246115 | chemokine (C-X-C motif) ligand 12 | sphingosine-1-phosphate receptor 4; Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes | 0.900 |
CXCL12 | S1PR5 | ENSP00000379140 | ENSP00000328472 | chemokine (C-X-C motif) ligand 12 | sphingosine-1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells | 0.910 |
CXCL13 | CNR1 | ENSP00000286758 | ENSP00000358511 | chemokine (C-X-C motif) ligand 13; Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5 | cannabinoid receptor 1 (brain) | 0.907 |