| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BDH2 | CNGA2 | ENSP00000296424 | ENSP00000328478 | 3-hydroxybutyrate dehydrogenase, type 2; Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity) | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | 0.584 |
| BEST2 | CNGA2 | ENSP00000042931 | ENSP00000328478 | bestrophin 2; Forms calcium-sensitive chloride channels. Permeable to bicarbonate | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | 0.747 |
| CALM1 | CNGA2 | ENSP00000349467 | ENSP00000328478 | calmodulin 1 (phosphorylase kinase, delta) | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | 0.576 |
| CALM1 | NOS1 | ENSP00000349467 | ENSP00000337459 | calmodulin 1 (phosphorylase kinase, delta) | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | 0.806 |
| CALM1 | NOS3 | ENSP00000349467 | ENSP00000297494 | calmodulin 1 (phosphorylase kinase, delta) | nitric oxide synthase 3 (endothelial cell); Produces nitric oxide (NO) (By similarity) | 0.993 |
| CNGA2 | BDH2 | ENSP00000328478 | ENSP00000296424 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | 3-hydroxybutyrate dehydrogenase, type 2; Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity) | 0.584 |
| CNGA2 | BEST2 | ENSP00000328478 | ENSP00000042931 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | bestrophin 2; Forms calcium-sensitive chloride channels. Permeable to bicarbonate | 0.747 |
| CNGA2 | CALM1 | ENSP00000328478 | ENSP00000349467 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | calmodulin 1 (phosphorylase kinase, delta) | 0.576 |
| CNGA2 | KIRREL2 | ENSP00000328478 | ENSP00000353331 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | kin of IRRE like 2 (Drosophila) | 0.561 |
| CNGA2 | NOS1 | ENSP00000328478 | ENSP00000337459 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | 0.785 |
| CNGA2 | NOS3 | ENSP00000328478 | ENSP00000297494 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | nitric oxide synthase 3 (endothelial cell); Produces nitric oxide (NO) (By similarity) | 0.523 |
| CNGA2 | OMP | ENSP00000328478 | ENSP00000436376 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | olfactory marker protein; May act as a modulator of the olfactory signal- transduction cascade | 0.564 |
| CNGA2 | PEX5L | ENSP00000328478 | ENSP00000419975 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | peroxisomal biogenesis factor 5-like; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence (By similarity) | 0.649 |
| CNGA2 | RIC8B | ENSP00000328478 | ENSP00000376583 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans); Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP (By similarity). Able to potentiate G(olf)-alpha- dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction (By similarity) | 0.556 |
| CNGA2 | SLC9A3R1 | ENSP00000328478 | ENSP00000262613 | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli ( [...] | 0.566 |
| KIRREL2 | CNGA2 | ENSP00000353331 | ENSP00000328478 | kin of IRRE like 2 (Drosophila) | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | 0.561 |
| NOS1 | CALM1 | ENSP00000337459 | ENSP00000349467 | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | calmodulin 1 (phosphorylase kinase, delta) | 0.806 |
| NOS1 | CNGA2 | ENSP00000337459 | ENSP00000328478 | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | cyclic nucleotide gated channel alpha 2; Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons | 0.785 |
| NOS1 | NOS3 | ENSP00000337459 | ENSP00000297494 | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | nitric oxide synthase 3 (endothelial cell); Produces nitric oxide (NO) (By similarity) | 0.904 |
| NOS3 | CALM1 | ENSP00000297494 | ENSP00000349467 | nitric oxide synthase 3 (endothelial cell); Produces nitric oxide (NO) (By similarity) | calmodulin 1 (phosphorylase kinase, delta) | 0.993 |
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