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IMP4 IMP4 WDR36 WDR36 NOP14 NOP14 TBL3 TBL3 NOC4L NOC4L RRP9 RRP9 HEATR1 HEATR1 BYSL BYSL WDR75 WDR75 UTP15 UTP15 PWP2 PWP2
"NOC4L" - nucleolar complex associated 4 homolog (S. cerevisiae) in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOC4Lnucleolar complex associated 4 homolog (S. cerevisiae) (516 aa)    
Predicted Functional Partners:
PWP2
PWP2 periodic tryptophan protein homolog (yeast) (919 aa)
      score_image score_image   score_image   0.998
BYSL
bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa)
      score_image score_image   score_image   0.997
WDR36
WD repeat domain 36; Involved in T-cell activation and highly co-regulated with IL2 (951 aa)
      score_image score_image   score_image   0.996
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (475 aa)
      score_image score_image   score_image   0.996
HEATR1
HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) (2144 aa)
      score_image score_image   score_image   0.996
NOP14
NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity) (857 aa)
      score_image score_image   score_image   0.995
UTP15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae); Involved in nucleolar processing of pre-18S ribosomal RNA (By similarity) (518 aa)
      score_image score_image   score_image   0.995
IMP4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (291 aa)
      score_image score_image   score_image   0.994
TBL3
transducin (beta)-like 3 (808 aa)
      score_image score_image   score_image   0.993
WDR75
WD repeat domain 75 (830 aa)
      score_image score_image   score_image   0.993
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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