node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GABRA1 | GABRA5 | ENSP00000023897 | ENSP00000335592 | gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, alpha 5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.901 |
GABRA1 | GABRB2 | ENSP00000023897 | ENSP00000274547 | gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, beta 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.920 |
GABRA1 | GABRG2 | ENSP00000023897 | ENSP00000410732 | gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.914 |
GABRA1 | TRAK2 | ENSP00000023897 | ENSP00000328875 | gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity) | 0.908 |
GABRA5 | GABRA1 | ENSP00000335592 | ENSP00000023897 | gamma-aminobutyric acid (GABA) A receptor, alpha 5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.901 |
GABRA5 | GABRB2 | ENSP00000335592 | ENSP00000274547 | gamma-aminobutyric acid (GABA) A receptor, alpha 5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, beta 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.917 |
GABRA5 | GABRG2 | ENSP00000335592 | ENSP00000410732 | gamma-aminobutyric acid (GABA) A receptor, alpha 5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.910 |
GABRA5 | TRAK2 | ENSP00000335592 | ENSP00000328875 | gamma-aminobutyric acid (GABA) A receptor, alpha 5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity) | 0.821 |
GABRB2 | GABRA1 | ENSP00000274547 | ENSP00000023897 | gamma-aminobutyric acid (GABA) A receptor, beta 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.920 |
GABRB2 | GABRA5 | ENSP00000274547 | ENSP00000335592 | gamma-aminobutyric acid (GABA) A receptor, beta 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, alpha 5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.917 |
GABRB2 | GABRG2 | ENSP00000274547 | ENSP00000410732 | gamma-aminobutyric acid (GABA) A receptor, beta 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.914 |
GABRB2 | TRAK2 | ENSP00000274547 | ENSP00000328875 | gamma-aminobutyric acid (GABA) A receptor, beta 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity) | 0.978 |
GABRG2 | GABRA1 | ENSP00000410732 | ENSP00000023897 | gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.914 |
GABRG2 | GABRA5 | ENSP00000410732 | ENSP00000335592 | gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, alpha 5; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.910 |
GABRG2 | GABRB2 | ENSP00000410732 | ENSP00000274547 | gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | gamma-aminobutyric acid (GABA) A receptor, beta 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | 0.914 |
GABRG2 | TRAK2 | ENSP00000410732 | ENSP00000328875 | gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel | trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity) | 0.837 |
HGS | TRAK2 | ENSP00000331201 | ENSP00000328875 | hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down- regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity) | 0.826 |
KIF5B | RHOT1 | ENSP00000307078 | ENSP00000351132 | kinesin family member 5B; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity) | ras homolog family member T1; Mitochondrial GTPase involved in mitochondrial trafficking (By similarity) | 0.573 |
KIF5B | TRAK2 | ENSP00000307078 | ENSP00000328875 | kinesin family member 5B; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity) | trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity) | 0.833 |
KIF5C | RHOT1 | ENSP00000393379 | ENSP00000351132 | kinesin family member 5C | ras homolog family member T1; Mitochondrial GTPase involved in mitochondrial trafficking (By similarity) | 0.675 |