node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RAB27A | RIMS2 | ENSP00000337761 | ENSP00000384892 | RAB27A, member RAS oncogene family; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.564 |
RAB27A | RPH3AL | ENSP00000337761 | ENSP00000328977 | RAB27A, member RAS oncogene family; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse | rabphilin 3A-like (without C2 domains); Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells | 0.933 |
RAB27A | UNC13B | ENSP00000337761 | ENSP00000367756 | RAB27A, member RAS oncogene family; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.816 |
RAB27B | RPH3AL | ENSP00000262094 | ENSP00000328977 | RAB27B, member RAS oncogene family; May be involved in targeting uroplakins to urothelial apical membranes (By similarity) | rabphilin 3A-like (without C2 domains); Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells | 0.882 |
RAB27B | UNC13B | ENSP00000262094 | ENSP00000367756 | RAB27B, member RAS oncogene family; May be involved in targeting uroplakins to urothelial apical membranes (By similarity) | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.465 |
RAB3A | RIMS2 | ENSP00000222256 | ENSP00000384892 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.995 |
RAB3A | RPH3AL | ENSP00000222256 | ENSP00000328977 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | rabphilin 3A-like (without C2 domains); Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells | 0.867 |
RAB3A | SNAP25 | ENSP00000222256 | ENSP00000254976 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | synaptosomal-associated protein, 25kDa | 0.931 |
RAB3A | UNC13B | ENSP00000222256 | ENSP00000367756 | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.974 |
RAB3B | RIMS2 | ENSP00000360718 | ENSP00000384892 | RAB3B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.727 |
RAB3B | RPH3AL | ENSP00000360718 | ENSP00000328977 | RAB3B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | rabphilin 3A-like (without C2 domains); Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells | 0.835 |
RAB3B | UNC13B | ENSP00000360718 | ENSP00000367756 | RAB3B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.557 |
RAB3C | RIMS2 | ENSP00000282878 | ENSP00000384892 | RAB3C, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.929 |
RAB3C | RPH3AL | ENSP00000282878 | ENSP00000328977 | RAB3C, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | rabphilin 3A-like (without C2 domains); Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells | 0.879 |
RAB3C | UNC13B | ENSP00000282878 | ENSP00000367756 | RAB3C, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.532 |
RAB3D | RIMS2 | ENSP00000222120 | ENSP00000384892 | RAB3D, member RAS oncogene family; Protein transport. Probably involved in regulated exocytosis (By similarity) | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | 0.726 |
RAB3D | RPH3AL | ENSP00000222120 | ENSP00000328977 | RAB3D, member RAS oncogene family; Protein transport. Probably involved in regulated exocytosis (By similarity) | rabphilin 3A-like (without C2 domains); Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells | 0.835 |
RAB3D | UNC13B | ENSP00000222120 | ENSP00000367756 | RAB3D, member RAS oncogene family; Protein transport. Probably involved in regulated exocytosis (By similarity) | unc-13 homolog B (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity) | 0.626 |
RIMS2 | RAB27A | ENSP00000384892 | ENSP00000337761 | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | RAB27A, member RAS oncogene family; Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse | 0.564 |
RIMS2 | RAB3A | ENSP00000384892 | ENSP00000222256 | regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein | RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal | 0.995 |