FAM174B protein (Homo sapiens) - STRING network view

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Score

FAM174B

family with sequence similarity 174, member B (159 aa)

Predicted Functional Partners:

LIPT1

0.678

TXNDC9

0.664

TMEM132C

0.535

ERG

0.450

AR

0.450

KIAA1467

0.424

FAM20C

0.412

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ERG	ENSP00000363822	ENSP00000381891	androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3	v-ets erythroblastosis virus E26 oncogene homolog (avian); Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure	0.918
AR	FAM174B	ENSP00000363822	ENSP00000329040	androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3	family with sequence similarity 174, member B	0.450
ERG	AR	ENSP00000381891	ENSP00000363822	v-ets erythroblastosis virus E26 oncogene homolog (avian); Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure	androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3	0.918
ERG	FAM174B	ENSP00000381891	ENSP00000329040	v-ets erythroblastosis virus E26 oncogene homolog (avian); Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure	family with sequence similarity 174, member B	0.450
FAM174B	AR	ENSP00000329040	ENSP00000363822	family with sequence similarity 174, member B	androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3	0.450
FAM174B	ERG	ENSP00000329040	ENSP00000381891	family with sequence similarity 174, member B	v-ets erythroblastosis virus E26 oncogene homolog (avian); Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure	0.450
FAM174B	FAM20C	ENSP00000329040	ENSP00000322323	family with sequence similarity 174, member B	family with sequence similarity 20, member C; Calcium-binding kinase that phosphorylates the caseins and several secreted proteins implicated in biomineralization, including the secretory calcium binding phosphoproteins (SCPP). Preferencially phosphorylates its targets within the S-x-E/pS motif	0.412
FAM174B	KIAA1467	ENSP00000329040	ENSP00000197268	family with sequence similarity 174, member B	KIAA1467	0.424
FAM174B	LIPT1	ENSP00000329040	ENSP00000342071	family with sequence similarity 174, member B	lipoyltransferase 1; Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes (By similarity)	0.678
FAM174B	TMEM132C	ENSP00000329040	ENSP00000410852	family with sequence similarity 174, member B	transmembrane protein 132C	0.535
FAM174B	TXNDC9	ENSP00000329040	ENSP00000264255	family with sequence similarity 174, member B	thioredoxin domain containing 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin	0.664
FAM20C	FAM174B	ENSP00000322323	ENSP00000329040	family with sequence similarity 20, member C; Calcium-binding kinase that phosphorylates the caseins and several secreted proteins implicated in biomineralization, including the secretory calcium binding phosphoproteins (SCPP). Preferencially phosphorylates its targets within the S-x-E/pS motif	family with sequence similarity 174, member B	0.412
KIAA1467	FAM174B	ENSP00000197268	ENSP00000329040	KIAA1467	family with sequence similarity 174, member B	0.424
LIPT1	FAM174B	ENSP00000342071	ENSP00000329040	lipoyltransferase 1; Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes (By similarity)	family with sequence similarity 174, member B	0.678
LIPT1	TXNDC9	ENSP00000342071	ENSP00000264255	lipoyltransferase 1; Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes (By similarity)	thioredoxin domain containing 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin	0.735
TMEM132C	FAM174B	ENSP00000410852	ENSP00000329040	transmembrane protein 132C	family with sequence similarity 174, member B	0.535
TXNDC9	FAM174B	ENSP00000264255	ENSP00000329040	thioredoxin domain containing 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin	family with sequence similarity 174, member B	0.664
TXNDC9	LIPT1	ENSP00000264255	ENSP00000342071	thioredoxin domain containing 9; Significantly diminishes the chaperonin TCP1 complex ATPase activity, thus negatively impacts protein folding, including that of actin or tubulin	lipoyltransferase 1; Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes (By similarity)	0.735

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