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STRINGSTRING
KDM5C KDM5C HSFX2 HSFX2 PRY PRY HSFX1 HSFX1 HSFY1 HSFY1 RBMY1A1 RBMY1A1 BPY2 BPY2 CDYL2 CDYL2 MAP1S MAP1S UBE3A UBE3A
"BPY2" - basic charge, Y-linked, 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPY2basic charge, Y-linked, 2 (106 aa)    
Predicted Functional Partners:
PRY
PTPN13-like, Y-linked (147 aa)
            score_image   0.723
MAP1S
microtubule-associated protein 1S (1059 aa)
        score_image   score_image   0.715
HSFX2
heat shock transcription factor family, X linked 2 (423 aa)
            score_image   0.658
HSFX1
heat shock transcription factor family, X linked 1 (423 aa)
            score_image   0.658
UBE3A
ubiquitin protein ligase E3A (875 aa)
        score_image   score_image   0.649
CDYL2
chromodomain protein, Y-like 2 (506 aa)
            score_image   0.566
RBMY1A1
RNA binding motif protein, Y-linked, family 1, member A1; RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs (496 aa)
            score_image   0.506
KDM5C
lysine (K)-specific demethylase 5C; Histone demethylase that specifically demethylates ’Lys- 4’ of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ’Lys-9’, H3 ’Lys-27’, H3 ’Lys-36’, H3 ’Lys-79’ or H4 ’Lys-20’. Demethylates trimethylated and dimethylated but not monomethylated H3 ’Lys-4’. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (1560 aa)
            score_image   0.472
HSFY1
heat shock transcription factor, Y-linked 1 (401 aa)
            score_image   0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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