node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NMU | NPB | ENSP00000264218 | ENSP00000332766 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | 0.932 |
NMU | NPBWR1 | ENSP00000264218 | ENSP00000330284 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | neuropeptides B/W receptor 1; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B | 0.929 |
NMU | NPBWR2 | ENSP00000264218 | ENSP00000358783 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | neuropeptides B/W receptor 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals | 0.927 |
NMU | NPW | ENSP00000264218 | ENSP00000330070 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | neuropeptide W; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity). NPW23 activates GPR7 and GPR8 more efficiently than NPW30 | 0.948 |
NMU | NPY | ENSP00000264218 | ENSP00000242152 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone | 0.956 |
NMU | OPRD1 | ENSP00000264218 | ENSP00000234961 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | opioid receptor, delta 1; Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins | 0.901 |
NMU | OPRK1 | ENSP00000264218 | ENSP00000265572 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | opioid receptor, kappa 1; Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions | 0.907 |
NMU | OPRM1 | ENSP00000264218 | ENSP00000394624 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | opioid receptor, mu 1 | 0.914 |
NMU | POMC | ENSP00000264218 | ENSP00000264708 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol | 0.988 |
NMU | SST | ENSP00000264218 | ENSP00000287641 | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | somatostatin; Somatostatin inhibits the release of somatotropin | 0.938 |
NPB | NMU | ENSP00000332766 | ENSP00000264218 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder | 0.932 |
NPB | NPBWR1 | ENSP00000332766 | ENSP00000330284 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | neuropeptides B/W receptor 1; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B | 0.997 |
NPB | NPBWR2 | ENSP00000332766 | ENSP00000358783 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | neuropeptides B/W receptor 2; Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals | 0.994 |
NPB | NPW | ENSP00000332766 | ENSP00000330070 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | neuropeptide W; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity). NPW23 activates GPR7 and GPR8 more efficiently than NPW30 | 0.988 |
NPB | NPY | ENSP00000332766 | ENSP00000242152 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone | 0.930 |
NPB | OPRD1 | ENSP00000332766 | ENSP00000234961 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | opioid receptor, delta 1; Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. receptor for enkephalins | 0.937 |
NPB | OPRK1 | ENSP00000332766 | ENSP00000265572 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | opioid receptor, kappa 1; Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions | 0.945 |
NPB | OPRM1 | ENSP00000332766 | ENSP00000394624 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | opioid receptor, mu 1 | 0.941 |
NPB | POMC | ENSP00000332766 | ENSP00000264708 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol | 0.916 |
NPB | SST | ENSP00000332766 | ENSP00000287641 | neuropeptide B; May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway (By similarity) | somatostatin; Somatostatin inhibits the release of somatotropin | 0.925 |