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STRINGSTRING
KIF14 KIF14 LINGO3 LINGO3 DHX8 DHX8 DDX59 DDX59 RPF2 RPF2 DDX54 DDX54 DDX60L DDX60L NSUN6 NSUN6 NOP2 NOP2 YTHDC2 YTHDC2 DDX28 DDX28
"DDX59" - DEAD in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX59DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 (619 aa)    
Predicted Functional Partners:
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (1220 aa)
score_image     score_image score_image   score_image   0.841
LINGO3
leucine rich repeat and Ig domain containing 3 (592 aa)
            score_image   0.817
NOP2
NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase (808 aa)
      score_image score_image   score_image   0.691
NSUN6
NOP2/Sun domain family, member 6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential) (469 aa)
      score_image score_image   score_image   0.691
YTHDC2
YTH domain containing 2 (1430 aa)
      score_image score_image   score_image   0.687
RPF2
ribosome production factor 2 homolog (S. cerevisiae) (306 aa)
      score_image score_image   score_image   0.683
DDX54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors (882 aa)
    score_image score_image score_image   score_image score_image 0.675
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like (1706 aa)
      score_image score_image   score_image   0.675
KIF14
kinesin family member 14; Plays an essential role in cytokinesis (1648 aa)
        score_image   score_image   0.661
DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28; May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (540 aa)
    score_image score_image score_image   score_image score_image 0.643
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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