node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACACA | ACACB | ENSP00000344789 | ENSP00000341044 | acetyl-CoA carboxylase alpha | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.999 |
ACACA | AMY1B | ENSP00000344789 | ENSP00000330484 | acetyl-CoA carboxylase alpha | amylase, alpha 1B (salivary) | 0.508 |
ACACA | PYGB | ENSP00000344789 | ENSP00000216962 | acetyl-CoA carboxylase alpha | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.421 |
ACACA | PYGL | ENSP00000344789 | ENSP00000216392 | acetyl-CoA carboxylase alpha | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.439 |
ACACA | PYGM | ENSP00000344789 | ENSP00000164139 | acetyl-CoA carboxylase alpha | phosphorylase, glycogen, muscle; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.423 |
ACACA | UMPS | ENSP00000344789 | ENSP00000232607 | acetyl-CoA carboxylase alpha | uridine monophosphate synthetase | 0.632 |
ACACB | ACACA | ENSP00000341044 | ENSP00000344789 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acetyl-CoA carboxylase alpha | 0.999 |
ACACB | AMY1B | ENSP00000341044 | ENSP00000330484 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | amylase, alpha 1B (salivary) | 0.538 |
ACACB | PYGB | ENSP00000341044 | ENSP00000216962 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.487 |
ACACB | PYGL | ENSP00000341044 | ENSP00000216392 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.476 |
ACACB | PYGM | ENSP00000341044 | ENSP00000164139 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | phosphorylase, glycogen, muscle; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.486 |
ACACB | UMPS | ENSP00000341044 | ENSP00000232607 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | uridine monophosphate synthetase | 0.635 |
AMY1B | ACACA | ENSP00000330484 | ENSP00000344789 | amylase, alpha 1B (salivary) | acetyl-CoA carboxylase alpha | 0.508 |
AMY1B | ACACB | ENSP00000330484 | ENSP00000341044 | amylase, alpha 1B (salivary) | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.538 |
AMY1B | BPI | ENSP00000330484 | ENSP00000262865 | amylase, alpha 1B (salivary) | bactericidal/permeability-increasing protein | 0.610 |
AMY1B | CDK2AP1 | ENSP00000330484 | ENSP00000261692 | amylase, alpha 1B (salivary) | cyclin-dependent kinase 2 associated protein 1; specific inhibitor of the cell-cycle kinase CDK2 (By similarity) | 0.517 |
AMY1B | GBE1 | ENSP00000330484 | ENSP00000410833 | amylase, alpha 1B (salivary) | glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells | 0.616 |
AMY1B | LCT | ENSP00000330484 | ENSP00000264162 | amylase, alpha 1B (salivary) | lactase; LPH splits lactose in the small intestine | 0.726 |
AMY1B | PYGB | ENSP00000330484 | ENSP00000216962 | amylase, alpha 1B (salivary) | phosphorylase, glycogen; brain; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.551 |
AMY1B | PYGL | ENSP00000330484 | ENSP00000216392 | amylase, alpha 1B (salivary) | phosphorylase, glycogen, liver; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) | 0.579 |