| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AP1S3 | GNB4 | ENSP00000379891 | ENSP00000232564 | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | 0.460 |
| AP1S3 | LRRC33 | ENSP00000379891 | ENSP00000328625 | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | leucine rich repeat containing 33 | 0.580 |
| AP1S3 | ZDHHC23 | ENSP00000379891 | ENSP00000330485 | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.609 |
| GK5 | ZDHHC23 | ENSP00000418001 | ENSP00000330485 | glycerol kinase 5 (putative) | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.711 |
| GNB4 | AP1S3 | ENSP00000232564 | ENSP00000379891 | guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.460 |
| GNB4 | LRRC33 | ENSP00000232564 | ENSP00000328625 | guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | leucine rich repeat containing 33 | 0.588 |
| GNB4 | ZDHHC23 | ENSP00000232564 | ENSP00000330485 | guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.553 |
| INS | NOS1 | ENSP00000250971 | ENSP00000337459 | insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity) | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | 0.418 |
| INS | ZDHHC23 | ENSP00000250971 | ENSP00000330485 | insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity) | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.539 |
| LRRC33 | AP1S3 | ENSP00000328625 | ENSP00000379891 | leucine rich repeat containing 33 | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.580 |
| LRRC33 | GNB4 | ENSP00000328625 | ENSP00000232564 | leucine rich repeat containing 33 | guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | 0.588 |
| LRRC33 | ZDHHC23 | ENSP00000328625 | ENSP00000330485 | leucine rich repeat containing 33 | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.562 |
| NOB1 | ZDHHC23 | ENSP00000268802 | ENSP00000330485 | NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); May play a role in mRNA degradation | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.775 |
| NOS1 | INS | ENSP00000337459 | ENSP00000250971 | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity) | 0.418 |
| NOS1 | ZDHHC23 | ENSP00000337459 | ENSP00000330485 | nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.607 |
| ZDHHC22 | ZDHHC23 | ENSP00000318222 | ENSP00000330485 | zinc finger, DHHC-type containing 22 | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | 0.673 |
| ZDHHC23 | AP1S3 | ENSP00000330485 | ENSP00000379891 | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.609 |
| ZDHHC23 | GK5 | ENSP00000330485 | ENSP00000418001 | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | glycerol kinase 5 (putative) | 0.711 |
| ZDHHC23 | GNB4 | ENSP00000330485 | ENSP00000232564 | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | 0.553 |
| ZDHHC23 | INS | ENSP00000330485 | ENSP00000250971 | zinc finger, DHHC-type containing 23; May be involved in NOS1 regulation and targeting to the synaptic membrane (By similarity) | insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity) | 0.539 |
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