Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | CXorf38 | chromosome X open reading frame 38 (319 aa) | ||||||||||||
Predicted Functional Partners:
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 | C11orf49 | chromosome 11 open reading frame 49 (337 aa) |
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0.593 | ||||||||||
 | SLC52A3 | solute carrier family 52, riboflavin transporter, member 3; Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), and to a lesser extent by amiloride (469 aa) |
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0.573 | ||||||||||
 | GTF2A1 | general transcription factor IIA, 1, 19/37kDa; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity (376 aa) |
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0.570 | ||||||||||
 | CCDC174 | coiled-coil domain containing 174 (467 aa) |
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0.561 | ||||||||||
 | DPYD | dihydropyrimidine dehydrogenase (1025 aa) |
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0.532 | ||||||||||
 | SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2; May participate in diverse steps of neurogenesis. Binds calcium (424 aa) |
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0.510 | ||||||||||
 | C21orf128 | chromosome 21 open reading frame 128 (162 aa) |
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0.509 | ||||||||||
 | TOMM40L | translocase of outer mitochondrial membrane 40 homolog (yeast)-like; Potential channel-forming protein implicated in import of protein precursors into mitochondria (By similarity) (308 aa) |
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0.501 | ||||||||||
 | CXorf26 | chromosome X open reading frame 26 (233 aa) |
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0.485 | ||||||||||
 | UBC | ubiquitin C (685 aa) |
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0.483 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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