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STRINGSTRING
TAPBPL TAPBPL TMEM41A TMEM41A SEC11C SEC11C ZNF358 ZNF358 UBC UBC METTL7A METTL7A PLSCR4 PLSCR4 DHRS2 DHRS2 FAF2 FAF2 WDFY4 WDFY4 ZCCHC2 ZCCHC2
"METTL7A" - methyltransferase like 7A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL7Amethyltransferase like 7A; Probable methyltransferase (By similarity) (244 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.800
FAF2
Fas associated factor family member 2; May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome (445 aa)
            score_image   0.617
TMEM41A
transmembrane protein 41A (264 aa)
            score_image   0.593
SEC11C
SEC11 homolog C (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) (192 aa)
            score_image   0.507
ZCCHC2
zinc finger, CCHC domain containing 2 (1178 aa)
            score_image   0.494
TAPBPL
TAP binding protein-like (468 aa)
            score_image   0.491
ZNF358
zinc finger protein 358; May be involved in transcriptional regulation (568 aa)
            score_image   0.479
WDFY4
WDFY family member 4 (3184 aa)
            score_image   0.454
DHRS2
dehydrogenase/reductase (SDR family) member 2; Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication (300 aa)
            score_image   0.419
PLSCR4
phospholipid scramblase 4; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system (329 aa)
            score_image   0.412
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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