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STRINGSTRING
ZNF211 ZNF211 MEFV MEFV CASP1 CASP1 NLRP9 NLRP9 PRRC2C PRRC2C AIDA AIDA PSTPIP2 PSTPIP2
"NLRP9" - NLR family, pyrin domain containing 9 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
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protein homology
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Score
NLRP9NLR family, pyrin domain containing 9; Involved in inflammation (Potential) (991 aa)    
Predicted Functional Partners:
MEFV
Mediterranean fever; Probably controls the inflammatory response in myelomonocytic cells at the level of the cytoskeleton organization (781 aa)
            score_image   0.745
CASP1
caspase 1, apoptosis-related cysteine peptidase; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis (404 aa)
            score_image   0.487
PRRC2C
proline-rich coiled-coil 2C (2817 aa)
            score_image   0.467
PSTPIP2
proline-serine-threonine phosphatase interacting protein 2; Binds to F-actin. May be involved in regulation of the actin cytoskeleton (By similarity) (334 aa)
            score_image   0.456
ZNF211
zinc finger protein 211 (577 aa)
            score_image   0.418
AIDA
axin interactor, dorsalization associated; Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity) (306 aa)
            score_image   0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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