Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTRT1 | WSCD2 | ENSP00000360165 | ENSP00000331933 | actin-related protein T1 | WSC domain containing 2 | 0.543 |
ARHGEF28 | WSCD2 | ENSP00000411459 | ENSP00000331933 | Rho guanine nucleotide exchange factor (GEF) 28; Functions as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Functions in axonal branching, synapse formation and dendritic morphogenesis. Functions also in focal adhesion formation, cell motility and B-lymphocytes activation. May regulate NEFL expression and aggregation and play a role in apoptosis (By similarity) | WSC domain containing 2 | 0.584 |
ARHGEF3 | WSCD2 | ENSP00000341071 | ENSP00000331933 | Rho guanine nucleotide exchange factor (GEF) 3 | WSC domain containing 2 | 0.584 |
ITSN1 | WSCD2 | ENSP00000370719 | ENSP00000331933 | intersectin 1 (SH3 domain protein); Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1 | WSC domain containing 2 | 0.584 |
ITSN2 | WSCD2 | ENSP00000347244 | ENSP00000331933 | intersectin 2; Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR) | WSC domain containing 2 | 0.584 |
NET1 | WSCD2 | ENSP00000347134 | ENSP00000331933 | neuroepithelial cell transforming 1; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death | WSC domain containing 2 | 0.584 |
PGLYRP3 | WSCD2 | ENSP00000290722 | ENSP00000331933 | peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity | WSC domain containing 2 | 0.592 |
PGLYRP3 | ZC3H7B | ENSP00000290722 | ENSP00000263243 | peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity | zinc finger CCCH-type containing 7B | 0.485 |
TTC23L | WSCD2 | ENSP00000422188 | ENSP00000331933 | tetratricopeptide repeat domain 23-like | WSC domain containing 2 | 0.580 |
TTC23L | ZNF566 | ENSP00000422188 | ENSP00000376010 | tetratricopeptide repeat domain 23-like | zinc finger protein 566; May be involved in transcriptional regulation | 0.627 |
WSCD2 | ACTRT1 | ENSP00000331933 | ENSP00000360165 | WSC domain containing 2 | actin-related protein T1 | 0.543 |
WSCD2 | ARHGEF28 | ENSP00000331933 | ENSP00000411459 | WSC domain containing 2 | Rho guanine nucleotide exchange factor (GEF) 28; Functions as a RHOA-specific guanine nucleotide exchange factor regulating signaling pathways downstream of integrins and growth factor receptors. Functions in axonal branching, synapse formation and dendritic morphogenesis. Functions also in focal adhesion formation, cell motility and B-lymphocytes activation. May regulate NEFL expression and aggregation and play a role in apoptosis (By similarity) | 0.584 |
WSCD2 | ARHGEF3 | ENSP00000331933 | ENSP00000341071 | WSC domain containing 2 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.584 |
WSCD2 | ITSN1 | ENSP00000331933 | ENSP00000370719 | WSC domain containing 2 | intersectin 1 (SH3 domain protein); Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1 | 0.584 |
WSCD2 | ITSN2 | ENSP00000331933 | ENSP00000347244 | WSC domain containing 2 | intersectin 2; Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR) | 0.584 |
WSCD2 | NET1 | ENSP00000331933 | ENSP00000347134 | WSC domain containing 2 | neuroepithelial cell transforming 1; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death | 0.584 |
WSCD2 | PGLYRP3 | ENSP00000331933 | ENSP00000290722 | WSC domain containing 2 | peptidoglycan recognition protein 3; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity | 0.592 |
WSCD2 | TTC23L | ENSP00000331933 | ENSP00000422188 | WSC domain containing 2 | tetratricopeptide repeat domain 23-like | 0.580 |
WSCD2 | ZC3H7B | ENSP00000331933 | ENSP00000263243 | WSC domain containing 2 | zinc finger CCCH-type containing 7B | 0.588 |
WSCD2 | ZNF566 | ENSP00000331933 | ENSP00000376010 | WSC domain containing 2 | zinc finger protein 566; May be involved in transcriptional regulation | 0.641 |
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