LSMD1 protein (Homo sapiens) - STRING network view

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LSMD1

LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues (173 aa)

Predicted Functional Partners:

NAA35

0.969

NAA30

0.968

NAA11

0.910

NAA15

0.901

NAA16

0.749

UBC

0.721

NAA10

0.720

N4BP2L2

0.590

RPL26

0.566

SLC7A6OS

0.506

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSMD1	N4BP2L2	ENSP00000332103	ENSP00000382328	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	NEDD4 binding protein 2-like 2	0.590
LSMD1	NAA10	ENSP00000332103	ENSP00000417763	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	0.720
LSMD1	NAA11	ENSP00000332103	ENSP00000286794	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	N(alpha)-acetyltransferase 11, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity	0.910
LSMD1	NAA15	ENSP00000332103	ENSP00000296543	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	N(alpha)-acetyltransferase 15, NatA auxiliary subunit; The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter	0.901
LSMD1	NAA16	ENSP00000332103	ENSP00000368716	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity)	0.749
LSMD1	NAA30	ENSP00000332103	ENSP00000452521	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	N(alpha)-acetyltransferase 30, NatC catalytic subunit; Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B	0.968
LSMD1	NAA35	ENSP00000332103	ENSP00000354972	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	N(alpha)-acetyltransferase 35, NatC auxiliary subunit; Regulates proliferation of smooth muscle cells (By similarity). Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	0.969
LSMD1	RPL26	ENSP00000332103	ENSP00000293842	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	ribosomal protein L26	0.566
LSMD1	SLC7A6OS	ENSP00000332103	ENSP00000263997	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	solute carrier family 7, member 6 opposite strand; Directs RNA polymerase II nuclear import (By similarity)	0.506
LSMD1	UBC	ENSP00000332103	ENSP00000344818	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	ubiquitin C	0.721
N4BP2L2	LSMD1	ENSP00000382328	ENSP00000332103	NEDD4 binding protein 2-like 2	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	0.590
N4BP2L2	UBC	ENSP00000382328	ENSP00000344818	NEDD4 binding protein 2-like 2	ubiquitin C	0.538
NAA10	LSMD1	ENSP00000417763	ENSP00000332103	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	0.720
NAA10	NAA11	ENSP00000417763	ENSP00000286794	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	N(alpha)-acetyltransferase 11, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity	0.723
NAA10	NAA15	ENSP00000417763	ENSP00000296543	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	N(alpha)-acetyltransferase 15, NatA auxiliary subunit; The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter	0.989
NAA10	NAA16	ENSP00000417763	ENSP00000368716	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity)	0.980
NAA10	NAA30	ENSP00000417763	ENSP00000452521	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	N(alpha)-acetyltransferase 30, NatC catalytic subunit; Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. Necessary for the lysosomal localization and function of ARL8B	0.779
NAA10	NAA35	ENSP00000417763	ENSP00000354972	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	N(alpha)-acetyltransferase 35, NatC auxiliary subunit; Regulates proliferation of smooth muscle cells (By similarity). Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	0.869
NAA10	RPL26	ENSP00000417763	ENSP00000293842	N(alpha)-acetyltransferase 10, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration	ribosomal protein L26	0.599
NAA11	LSMD1	ENSP00000286794	ENSP00000332103	N(alpha)-acetyltransferase 11, NatA catalytic subunit; In complex with NAA15, displays alpha (N-terminal) acetyltransferase activity	LSM domain containing 1; Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues	0.910

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