| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LAP3 | P4HA3 | ENSP00000226299 | ENSP00000332170 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.900 |
| LAP3 | P5CR2 | ENSP00000226299 | ENSP00000414068 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | Uncharacterized protein | 0.908 |
| LAP3 | PYCR1 | ENSP00000226299 | ENSP00000328858 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | pyrroline-5-carboxylate reductase 1; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress | 0.929 |
| LAP3 | PYCRL | ENSP00000226299 | ENSP00000220966 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | pyrroline-5-carboxylate reductase-like | 0.908 |
| MYCBPAP | P4HA3 | ENSP00000323184 | ENSP00000332170 | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.669 |
| P4HA3 | LAP3 | ENSP00000332170 | ENSP00000226299 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | 0.900 |
| P4HA3 | MYCBPAP | ENSP00000332170 | ENSP00000323184 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | MYCBP associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) | 0.669 |
| P4HA3 | P4HB | ENSP00000332170 | ENSP00000327801 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] | 0.970 |
| P4HA3 | P5CR2 | ENSP00000332170 | ENSP00000414068 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | Uncharacterized protein | 0.900 |
| P4HA3 | PDIA2 | ENSP00000332170 | ENSP00000219406 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | protein disulfide isomerase family A, member 2; Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins | 0.651 |
| P4HA3 | PRODH2 | ENSP00000332170 | ENSP00000301175 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | proline dehydrogenase (oxidase) 2; Converts proline to delta-1-pyrroline-5-carboxylate (Probable) | 0.900 |
| P4HA3 | PYCR1 | ENSP00000332170 | ENSP00000328858 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | pyrroline-5-carboxylate reductase 1; Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress | 0.900 |
| P4HA3 | PYCRL | ENSP00000332170 | ENSP00000220966 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | pyrroline-5-carboxylate reductase-like | 0.900 |
| P4HA3 | SLC2A12 | ENSP00000332170 | ENSP00000275230 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | solute carrier family 2 (facilitated glucose transporter), member 12; Facilitative glucose transporter (By similarity) | 0.646 |
| P4HA3 | ZNF469 | ENSP00000332170 | ENSP00000402343 | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | zinc finger protein 469; May be involved in transcriptional regulation | 0.636 |
| P4HB | P4HA3 | ENSP00000327801 | ENSP00000332170 | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.970 |
| P4HB | PDIA2 | ENSP00000327801 | ENSP00000219406 | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] | protein disulfide isomerase family A, member 2; Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins | 0.586 |
| P5CR2 | LAP3 | ENSP00000414068 | ENSP00000226299 | Uncharacterized protein | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | 0.908 |
| P5CR2 | P4HA3 | ENSP00000414068 | ENSP00000332170 | Uncharacterized protein | prolyl 4-hydroxylase, alpha polypeptide III; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins | 0.900 |
| P5CR2 | PRODH2 | ENSP00000414068 | ENSP00000301175 | Uncharacterized protein | proline dehydrogenase (oxidase) 2; Converts proline to delta-1-pyrroline-5-carboxylate (Probable) | 0.693 |
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