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ADH5 ADH5 ADH4 ADH4 ADH7 ADH7 GAD1 GAD1 ALDH1A3 ALDH1A3 ACSS2 ACSS2 ABAT ABAT ACSS1 ACSS1 ADH6 ADH6 ADH1B ADH1B ADH1A ADH1A
"ALDH1A3" - aldehyde dehydrogenase 1 family, member A3 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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ALDH1A3aldehyde dehydrogenase 1 family, member A3; Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity) (512 aa)    
Predicted Functional Partners:
ACSS1
acyl-CoA synthetase short-chain family member 1 (689 aa)
      score_image score_image score_image score_image   0.958
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide (375 aa)
          score_image score_image   0.958
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide (375 aa)
          score_image score_image   0.957
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide (380 aa)
          score_image score_image   0.955
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide; Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism (394 aa)
          score_image score_image   0.955
ADH5
alcohol dehydrogenase 5 (class III), chi polypeptide; Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (374 aa)
          score_image score_image   0.954
ACSS2
acyl-CoA synthetase short-chain family member 2; Activates acetate so that it can be used for lipid synthesis or for energy generation (714 aa)
      score_image score_image score_image score_image   0.952
ADH6
alcohol dehydrogenase 6 (class V) (375 aa)
          score_image score_image   0.949
ABAT
4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (500 aa)
score_image     score_image score_image score_image score_image   0.943
GAD1
glutamate decarboxylase 1 (brain, 67kDa); Catalyzes the production of GABA (594 aa)
      score_image score_image score_image score_image   0.928
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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