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STRINGSTRING
CCL27 CCL27 CCL25 CCL25 CCR10 CCR10 LPAR1 LPAR1 CCL28 CCL28 CXCL12 CXCL12 CCL21 CCL21 CCR7 CCR7 CCL19 CCL19 CXCL11 CXCL11 CXCL13 CXCL13
"CCR10" - chemokine (C-C motif) receptor 10 in Homo sapiens
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Predicted Interactions
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Score
CCR10chemokine (C-C motif) receptor 10; Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line (362 aa)    
Predicted Functional Partners:
CCL27
chemokine (C-C motif) ligand 27; Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10 (112 aa)
        score_image score_image score_image   0.998
CCL28
chemokine (C-C motif) ligand 28; Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner (127 aa)
        score_image score_image score_image   0.985
CCL25
chemokine (C-C motif) ligand 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1 (150 aa)
        score_image score_image score_image   0.973
CCL21
chemokine (C-C motif) ligand 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs (134 aa)
        score_image score_image score_image   0.967
CXCL12
chemokine (C-X-C motif) ligand 12 (140 aa)
        score_image score_image score_image   0.966
CCL19
chemokine (C-C motif) ligand 19; May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes (98 aa)
        score_image score_image score_image   0.963
CCR7
chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions (378 aa)
        score_image score_image score_image score_image 0.957
CXCL13
chemokine (C-X-C motif) ligand 13; Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B- lymphocytes. Binds to BLR1/CXCR5 (109 aa)
        score_image score_image     0.955
LPAR1
lysophosphatidic acid receptor 1; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation (364 aa)
          score_image score_image   0.925
CXCL11
chemokine (C-X-C motif) ligand 11; Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (94 aa)
          score_image score_image   0.917
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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