OTOP2 protein (Homo sapiens) - STRING network view

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OTOP2

otopetrin 2 (562 aa)

Predicted Functional Partners:

ENSG00000258417

0.639

USH1G

0.606

GPC2

0.577

OC90

0.561

TCTA

0.491

ATP2B2

0.476

TINAGL1

0.475

ATP2B4

0.418

ADAMTS15

0.413

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS15	OTOP2	ENSP00000299164	ENSP00000332528	ADAM metallopeptidase with thrombospondin type 1 motif, 15	otopetrin 2	0.413
ADAMTS15	USH1G	ENSP00000299164	ENSP00000320076	ADAM metallopeptidase with thrombospondin type 1 motif, 15	Usher syndrome 1G (autosomal recessive); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing	0.489
ATP2B2	ENSG00000258417	ENSP00000324172	ENSP00000262283	ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	Uncharacterized protein ; It is unlikely that this protein has phospholipase A2 activity	0.752
ATP2B2	OC90	ENSP00000324172	ENSP00000254627	ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	otoconin 90; It is unlikely that this protein has phospholipase A2 activity	0.747
ATP2B2	OTOP2	ENSP00000324172	ENSP00000332528	ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	otopetrin 2	0.476
ATP2B4	ENSG00000258417	ENSP00000350310	ENSP00000262283	ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	Uncharacterized protein ; It is unlikely that this protein has phospholipase A2 activity	0.743
ATP2B4	OC90	ENSP00000350310	ENSP00000254627	ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	otoconin 90; It is unlikely that this protein has phospholipase A2 activity	0.680
ATP2B4	OTOP2	ENSP00000350310	ENSP00000332528	ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	otopetrin 2	0.418
ENSG00000258417	ATP2B2	ENSP00000262283	ENSP00000324172	Uncharacterized protein ; It is unlikely that this protein has phospholipase A2 activity	ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	0.752
ENSG00000258417	ATP2B4	ENSP00000262283	ENSP00000350310	Uncharacterized protein ; It is unlikely that this protein has phospholipase A2 activity	ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	0.743
ENSG00000258417	OTOP2	ENSP00000262283	ENSP00000332528	Uncharacterized protein ; It is unlikely that this protein has phospholipase A2 activity	otopetrin 2	0.639
GPC2	OTOP2	ENSP00000292377	ENSP00000332528	glypican 2; Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity)	otopetrin 2	0.577
GPC2	TINAGL1	ENSP00000292377	ENSP00000271064	glypican 2; Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity)	tubulointerstitial nephritis antigen-like 1; May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein (By similarity)	0.441
GPC2	USH1G	ENSP00000292377	ENSP00000320076	glypican 2; Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity)	Usher syndrome 1G (autosomal recessive); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing	0.638
OC90	ATP2B2	ENSP00000254627	ENSP00000324172	otoconin 90; It is unlikely that this protein has phospholipase A2 activity	ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	0.747
OC90	ATP2B4	ENSP00000254627	ENSP00000350310	otoconin 90; It is unlikely that this protein has phospholipase A2 activity	ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	0.680
OC90	OTOP2	ENSP00000254627	ENSP00000332528	otoconin 90; It is unlikely that this protein has phospholipase A2 activity	otopetrin 2	0.561
OTOP2	ADAMTS15	ENSP00000332528	ENSP00000299164	otopetrin 2	ADAM metallopeptidase with thrombospondin type 1 motif, 15	0.413
OTOP2	ATP2B2	ENSP00000332528	ENSP00000324172	otopetrin 2	ATPase, Ca++ transporting, plasma membrane 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	0.476
OTOP2	ATP2B4	ENSP00000332528	ENSP00000350310	otopetrin 2	ATPase, Ca++ transporting, plasma membrane 4; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	0.418

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