Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | MRPL40 | mitochondrial ribosomal protein L40 (206 aa) | ||||||||||||
Predicted Functional Partners:
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 | MRPL19 | mitochondrial ribosomal protein L19 (292 aa) |
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0.995 | |||||||||
 | MRPL16 | mitochondrial ribosomal protein L16; Component of the large subunit of mitochondrial ribosome (251 aa) |
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0.995 | |||||||||
 | MRPL15 | mitochondrial ribosomal protein L15 (296 aa) |
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0.994 | |||||||||
 | MRPL32 | mitochondrial ribosomal protein L32 (188 aa) |
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0.976 | |||||||||
 | MRPL38 | mitochondrial ribosomal protein L38 (380 aa) |
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0.971 | |||||||||
 | MRPL27 | mitochondrial ribosomal protein L27 (148 aa) |
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0.970 | |||||||||
 | MRPL39 | mitochondrial ribosomal protein L39 (353 aa) |
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0.961 | |||||||||
 | MRPL46 | mitochondrial ribosomal protein L46 (279 aa) |
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0.959 | ||||||||
 | MRPL14 | mitochondrial ribosomal protein L14; Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable) (145 aa) |
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0.942 | |||||||||
 | MRPL21 | mitochondrial ribosomal protein L21 (205 aa) |
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0.942 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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