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KCNH1 KCNH1 KCNH5 KCNH5 KCNH2 KCNH2 KCNAB1 KCNAB1 KCNIP4 KCNIP4 KCND2 KCND2 KCNIP2 KCNIP2 KCNIP3 KCNIP3 KCNIP1 KCNIP1 NCS1 NCS1 DPP10 DPP10
"KCND2" - potassium voltage-gated channel, Shal-related subfamily, member 2 in Homo sapiens
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KCND2potassium voltage-gated channel, Shal-related subfamily, member 2; Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits (630 aa)    
Predicted Functional Partners:
KCNIP2
Kv channel interacting protein 2 (285 aa)
         score_image   score_image   0.999
KCNIP1
Kv channel interacting protein 1; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Seems to be involved in KCND2 trafficking to the cell surface (227 aa)
         score_image   score_image   0.998
KCNIP4
Kv channel interacting protein 4 (250 aa)
         score_image   score_image   0.987
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1 (1159 aa)
         score_image score_image score_image   0.984
KCNIP3
Kv channel interacting protein 3, calsenilin; Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity) (256 aa)
         score_image   score_image   0.979
DPP10
dipeptidyl-peptidase 10 (non-functional) (800 aa)
         score_image   score_image   0.976
NCS1
neuronal calcium sensor 1; Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N- type voltage-gated calcium channel (By similarity) (190 aa)
         score_image   score_image   0.973
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1; Pore-forming (alpha) subunit of voltage-gated non- inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts (989 aa)
         score_image score_image score_image   0.970
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1 (419 aa)
           score_image score_image   0.965
KCNH5
potassium voltage-gated channel, subfamily H (eag-related), member 5; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a non-inactivating outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly (988 aa)
         score_image score_image score_image   0.963
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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