| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADIPOR1 | C1QTNF9 | ENSP00000341785 | ENSP00000333737 | adiponectin receptor 1; Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | 0.862 |
| ANKRD53 | C1QTNF9 | ENSP00000353796 | ENSP00000333737 | ankyrin repeat domain 53 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | 0.472 |
| ANKRD53 | PCOTH | ENSP00000353796 | ENSP00000396192 | ankyrin repeat domain 53 | protein PCOTH isoform 1 ; May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway | 0.625 |
| BAD | C1QTNF9 | ENSP00000309103 | ENSP00000333737 | BCL2-associated agonist of cell death; Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | 0.815 |
| C1QTNF9 | ADIPOR1 | ENSP00000333737 | ENSP00000341785 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | adiponectin receptor 1; Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin | 0.862 |
| C1QTNF9 | ANKRD53 | ENSP00000333737 | ENSP00000353796 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | ankyrin repeat domain 53 | 0.472 |
| C1QTNF9 | BAD | ENSP00000333737 | ENSP00000309103 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | BCL2-associated agonist of cell death; Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways | 0.815 |
| C1QTNF9 | COLEC11 | ENSP00000333737 | ENSP00000339168 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | collectin sub-family member 11 | 0.425 |
| C1QTNF9 | KRTAP5-5 | ENSP00000333737 | ENSP00000382584 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | keratin associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | 0.501 |
| C1QTNF9 | OR10G7 | ENSP00000333737 | ENSP00000329689 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | olfactory receptor, family 10, subfamily G, member 7; Odorant receptor (Potential) | 0.471 |
| C1QTNF9 | OR13A1 | ENSP00000333737 | ENSP00000363522 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | olfactory receptor, family 13, subfamily A, member 1; Odorant receptor (Potential) | 0.502 |
| C1QTNF9 | OR2M4 | ENSP00000333737 | ENSP00000306688 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | olfactory receptor, family 2, subfamily M, member 4; Odorant receptor (Potential) | 0.472 |
| C1QTNF9 | PCOTH | ENSP00000333737 | ENSP00000396192 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | protein PCOTH isoform 1 ; May be involved in growth and survival of prostate cancer cells through the TAF-Ibeta pathway | 0.457 |
| C1QTNF9 | ZDHHC20 | ENSP00000333737 | ENSP00000371905 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | zinc finger, DHHC-type containing 20 | 0.470 |
| COLEC11 | C1QTNF9 | ENSP00000339168 | ENSP00000333737 | collectin sub-family member 11 | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | 0.425 |
| KRTAP5-5 | C1QTNF9 | ENSP00000382584 | ENSP00000333737 | keratin associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | C1q and tumor necrosis factor related protein 9; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity) | 0.501 |
| KRTAP5-5 | OR10G7 | ENSP00000382584 | ENSP00000329689 | keratin associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | olfactory receptor, family 10, subfamily G, member 7; Odorant receptor (Potential) | 0.658 |
| KRTAP5-5 | OR13A1 | ENSP00000382584 | ENSP00000363522 | keratin associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | olfactory receptor, family 13, subfamily A, member 1; Odorant receptor (Potential) | 0.702 |
| KRTAP5-5 | OR2M4 | ENSP00000382584 | ENSP00000306688 | keratin associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | olfactory receptor, family 2, subfamily M, member 4; Odorant receptor (Potential) | 0.660 |
| KRTAP5-5 | ZDHHC20 | ENSP00000382584 | ENSP00000371905 | keratin associated protein 5-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | zinc finger, DHHC-type containing 20 | 0.650 |
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