MRPL12 protein (Homo sapiens) - STRING network view

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Score

MRPL12

mitochondrial ribosomal protein L12 (198 aa)

Predicted Functional Partners:

MRPL3

0.995

RPLP0

0.992

MRTO4

0.992

MRPL1

0.989

RPL12

0.989

RPL11

0.989

RPL23

0.988

ICT1

0.987

MRPL11

0.986

MRPL33

0.977

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ICT1	MRPL1	ENSP00000301585	ENSP00000315017	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	mitochondrial ribosomal protein L1	0.453
ICT1	MRPL11	ENSP00000301585	ENSP00000308897	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	mitochondrial ribosomal protein L11	0.652
ICT1	MRPL12	ENSP00000301585	ENSP00000333837	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	mitochondrial ribosomal protein L12	0.987
ICT1	MRPL3	ENSP00000301585	ENSP00000264995	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	mitochondrial ribosomal protein L3	0.986
ICT1	RPL12	ENSP00000301585	ENSP00000354739	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	ribosomal protein L12; Binds directly to 26S ribosomal RNA (By similarity)	0.521
MRPL1	ICT1	ENSP00000315017	ENSP00000301585	mitochondrial ribosomal protein L1	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	0.453
MRPL1	MRPL11	ENSP00000315017	ENSP00000308897	mitochondrial ribosomal protein L1	mitochondrial ribosomal protein L11	0.999
MRPL1	MRPL12	ENSP00000315017	ENSP00000333837	mitochondrial ribosomal protein L1	mitochondrial ribosomal protein L12	0.989
MRPL1	MRPL3	ENSP00000315017	ENSP00000264995	mitochondrial ribosomal protein L1	mitochondrial ribosomal protein L3	0.993
MRPL1	MRPL33	ENSP00000315017	ENSP00000296102	mitochondrial ribosomal protein L1	mitochondrial ribosomal protein L33	0.907
MRPL1	MRTO4	ENSP00000315017	ENSP00000364320	mitochondrial ribosomal protein L1	mRNA turnover 4 homolog (S. cerevisiae); Involved in mRNA turnover and ribosome assembly (By similarity)	0.984
MRPL1	RPL11	ENSP00000315017	ENSP00000363676	mitochondrial ribosomal protein L1	ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity)	0.974
MRPL1	RPL12	ENSP00000315017	ENSP00000354739	mitochondrial ribosomal protein L1	ribosomal protein L12; Binds directly to 26S ribosomal RNA (By similarity)	0.993
MRPL1	RPL23	ENSP00000315017	ENSP00000377865	mitochondrial ribosomal protein L1	ribosomal protein L23	0.974
MRPL1	RPLP0	ENSP00000315017	ENSP00000339027	mitochondrial ribosomal protein L1	ribosomal protein, large, P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10 (By similarity)	0.982
MRPL11	ICT1	ENSP00000308897	ENSP00000301585	mitochondrial ribosomal protein L11	immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes	0.652
MRPL11	MRPL1	ENSP00000308897	ENSP00000315017	mitochondrial ribosomal protein L11	mitochondrial ribosomal protein L1	0.999
MRPL11	MRPL12	ENSP00000308897	ENSP00000333837	mitochondrial ribosomal protein L11	mitochondrial ribosomal protein L12	0.986
MRPL11	MRPL3	ENSP00000308897	ENSP00000264995	mitochondrial ribosomal protein L11	mitochondrial ribosomal protein L3	0.979
MRPL11	MRPL33	ENSP00000308897	ENSP00000296102	mitochondrial ribosomal protein L11	mitochondrial ribosomal protein L33	0.989

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