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STRINGSTRING
PLCXD1 PLCXD1 ZBED1 ZBED1 ARSD ARSD GYG2 GYG2 GTPBP6 GTPBP6 ASMTL ASMTL DHRSX DHRSX ASMT ASMT ACACB ACACB ACACA ACACA ACADM ACADM
"DHRSX" - dehydrogenase/reductase (SDR family) X-linked in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
DHRSXdehydrogenase/reductase (SDR family) X-linked (330 aa)    
Predicted Functional Partners:
GTPBP6
GTP binding protein 6 (putative) (287 aa)
      score_image     score_image   0.746
ZBED1
zinc finger, BED-type containing 1; Binds to 5’-TGTCG[CT]GA[CT]A-3’ DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity (694 aa)
            score_image   0.581
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
score_image           score_image   0.581
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
score_image           score_image   0.581
GYG2
glycogenin 2; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase (501 aa)
            score_image   0.563
ASMTL
acetylserotonin O-methyltransferase-like; Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity (621 aa)
            score_image   0.548
ARSD
arylsulfatase D (593 aa)
            score_image   0.506
ACADM
acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16 (425 aa)
            score_image   0.495
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1 (323 aa)
            score_image   0.484
ASMT
acetylserotonin O-methyltransferase; Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5- methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity (373 aa)
            score_image   0.459
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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