SAMD7 protein (Homo sapiens) - STRING network view

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SAMD7

sterile alpha motif domain containing 7 (446 aa)

Predicted Functional Partners:

PCBP4

0.575

ASF1B

0.541

HNRNPD

0.443

HNRPDL

0.424

SERPING1

0.424

DEFB108B

0.416

SKIL

0.402

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1B	PCBP4	ENSP00000263382	ENSP00000322341	ASF1 anti-silencing function 1 homolog B (S. cerevisiae); Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis	poly(rC) binding protein 4; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity)	0.418
ASF1B	SAMD7	ENSP00000263382	ENSP00000334668	ASF1 anti-silencing function 1 homolog B (S. cerevisiae); Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis	sterile alpha motif domain containing 7	0.541
DEFB108B	SAMD7	ENSP00000333234	ENSP00000334668	defensin, beta 108B; Has antibacterial activity (By similarity)	sterile alpha motif domain containing 7	0.416
HNRNPD	HNRPDL	ENSP00000313199	ENSP00000295470	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3’-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or [...]	0.909
HNRNPD	PCBP4	ENSP00000313199	ENSP00000322341	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	poly(rC) binding protein 4; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity)	0.404
HNRNPD	SAMD7	ENSP00000313199	ENSP00000334668	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	sterile alpha motif domain containing 7	0.443
HNRPDL	HNRNPD	ENSP00000295470	ENSP00000313199	heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3’-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or [...]	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.909
HNRPDL	SAMD7	ENSP00000295470	ENSP00000334668	heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3’-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or [...]	sterile alpha motif domain containing 7	0.424
PCBP4	ASF1B	ENSP00000322341	ENSP00000263382	poly(rC) binding protein 4; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity)	ASF1 anti-silencing function 1 homolog B (S. cerevisiae); Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis	0.418
PCBP4	HNRNPD	ENSP00000322341	ENSP00000313199	poly(rC) binding protein 4; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity)	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.404
PCBP4	SAMD7	ENSP00000322341	ENSP00000334668	poly(rC) binding protein 4; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity)	sterile alpha motif domain containing 7	0.575
SAMD7	ASF1B	ENSP00000334668	ENSP00000263382	sterile alpha motif domain containing 7	ASF1 anti-silencing function 1 homolog B (S. cerevisiae); Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis	0.541
SAMD7	DEFB108B	ENSP00000334668	ENSP00000333234	sterile alpha motif domain containing 7	defensin, beta 108B; Has antibacterial activity (By similarity)	0.416
SAMD7	HNRNPD	ENSP00000334668	ENSP00000313199	sterile alpha motif domain containing 7	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.443
SAMD7	HNRPDL	ENSP00000334668	ENSP00000295470	sterile alpha motif domain containing 7	heterogeneous nuclear ribonucleoprotein D-like; Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3’-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or [...]	0.424
SAMD7	PCBP4	ENSP00000334668	ENSP00000322341	sterile alpha motif domain containing 7	poly(rC) binding protein 4; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity)	0.575
SAMD7	SERPING1	ENSP00000334668	ENSP00000278407	sterile alpha motif domain containing 7	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	0.424
SAMD7	SKIL	ENSP00000334668	ENSP00000259119	sterile alpha motif domain containing 7	SKI-like oncogene; May have regulatory role in cell division or differentiation in response to extracellular signals	0.402
SERPING1	SAMD7	ENSP00000278407	ENSP00000334668	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	sterile alpha motif domain containing 7	0.424
SKIL	SAMD7	ENSP00000259119	ENSP00000334668	SKI-like oncogene; May have regulatory role in cell division or differentiation in response to extracellular signals	sterile alpha motif domain containing 7	0.402

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