| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEF1A1 | IGFN1 | ENSP00000330054 | ENSP00000334714 | eukaryotic translation elongation factor 1 alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production | immunoglobulin-like and fibronectin type III domain containing 1 | 0.831 |
| EEF1A2 | IGFN1 | ENSP00000217182 | ENSP00000334714 | eukaryotic translation elongation factor 1 alpha 2; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis | immunoglobulin-like and fibronectin type III domain containing 1 | 0.824 |
| IGFN1 | EEF1A1 | ENSP00000334714 | ENSP00000330054 | immunoglobulin-like and fibronectin type III domain containing 1 | eukaryotic translation elongation factor 1 alpha 1; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production | 0.831 |
| IGFN1 | EEF1A2 | ENSP00000334714 | ENSP00000217182 | immunoglobulin-like and fibronectin type III domain containing 1 | eukaryotic translation elongation factor 1 alpha 2; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis | 0.824 |
| IGFN1 | MEF2A | ENSP00000334714 | ENSP00000346389 | immunoglobulin-like and fibronectin type III domain containing 1 | myocyte enhancer factor 2A | 0.488 |
| IGFN1 | MEF2B | ENSP00000334714 | ENSP00000162023 | immunoglobulin-like and fibronectin type III domain containing 1 | myocyte enhancer factor 2B; Transcriptional activator which binds specifically to the MEF2 element, 5’-YTA[AT](4)TAR-3’, found in numerous muscle- specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription | 0.488 |
| IGFN1 | MEF2C | ENSP00000334714 | ENSP00000340874 | immunoglobulin-like and fibronectin type III domain containing 1 | myocyte enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platel [...] | 0.488 |
| IGFN1 | MEF2D | ENSP00000334714 | ENSP00000271555 | immunoglobulin-like and fibronectin type III domain containing 1 | myocyte enhancer factor 2D; Transcriptional activator which binds specifically to the MEF2 element, 5’-YTA[AT](4)TAR-3’, found in numerous muscle- specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity) | 0.488 |
| IGFN1 | MSS51 | ENSP00000334714 | ENSP00000299432 | immunoglobulin-like and fibronectin type III domain containing 1 | MSS51 mitochondrial translational activator homolog (S. cerevisiae) | 0.489 |
| IGFN1 | MYL5 | ENSP00000334714 | ENSP00000383023 | immunoglobulin-like and fibronectin type III domain containing 1 | myosin, light chain 5, regulatory | 0.471 |
| IGFN1 | RNPEP | ENSP00000334714 | ENSP00000295640 | immunoglobulin-like and fibronectin type III domain containing 1 | arginyl aminopeptidase (aminopeptidase B); Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin and Arg(- 1)-Lys(0)-somatostatin-14. Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4) (By similarity) | 0.586 |
| IGFN1 | RNPEPL1 | ENSP00000334714 | ENSP00000270357 | immunoglobulin-like and fibronectin type III domain containing 1 | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.546 |
| MEF2A | IGFN1 | ENSP00000346389 | ENSP00000334714 | myocyte enhancer factor 2A | immunoglobulin-like and fibronectin type III domain containing 1 | 0.488 |
| MEF2A | MEF2C | ENSP00000346389 | ENSP00000340874 | myocyte enhancer factor 2A | myocyte enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platel [...] | 0.904 |
| MEF2A | MEF2D | ENSP00000346389 | ENSP00000271555 | myocyte enhancer factor 2A | myocyte enhancer factor 2D; Transcriptional activator which binds specifically to the MEF2 element, 5’-YTA[AT](4)TAR-3’, found in numerous muscle- specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity) | 0.991 |
| MEF2B | IGFN1 | ENSP00000162023 | ENSP00000334714 | myocyte enhancer factor 2B; Transcriptional activator which binds specifically to the MEF2 element, 5’-YTA[AT](4)TAR-3’, found in numerous muscle- specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription | immunoglobulin-like and fibronectin type III domain containing 1 | 0.488 |
| MEF2C | IGFN1 | ENSP00000340874 | ENSP00000334714 | myocyte enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platel [...] | immunoglobulin-like and fibronectin type III domain containing 1 | 0.488 |
| MEF2C | MEF2A | ENSP00000340874 | ENSP00000346389 | myocyte enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platel [...] | myocyte enhancer factor 2A | 0.904 |
| MEF2C | MEF2D | ENSP00000340874 | ENSP00000271555 | myocyte enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platel [...] | myocyte enhancer factor 2D; Transcriptional activator which binds specifically to the MEF2 element, 5’-YTA[AT](4)TAR-3’, found in numerous muscle- specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity) | 0.956 |
| MEF2D | IGFN1 | ENSP00000271555 | ENSP00000334714 | myocyte enhancer factor 2D; Transcriptional activator which binds specifically to the MEF2 element, 5’-YTA[AT](4)TAR-3’, found in numerous muscle- specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity) | immunoglobulin-like and fibronectin type III domain containing 1 | 0.488 |
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