FAM91A1 protein (Homo sapiens) - STRING network view

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[Homology]

Score

FAM91A1

family with sequence similarity 91, member A1 (838 aa)

Predicted Functional Partners:

UBC

0.795

C8orf76

0.565

WDR67

0.561

IMPAD1

0.505

SKA2

0.470

MRPS23

0.450

DEPDC1B

0.450

DCAF13

0.433

MTL5

0.429

NUDCD1

0.416

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C8orf76	DCAF13	ENSP00000276704	ENSP00000297579	chromosome 8 open reading frame 76	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	0.412
C8orf76	FAM91A1	ENSP00000276704	ENSP00000335082	chromosome 8 open reading frame 76	family with sequence similarity 91, member A1	0.565
C8orf76	MRPS23	ENSP00000276704	ENSP00000320184	chromosome 8 open reading frame 76	mitochondrial ribosomal protein S23	0.418
C8orf76	SKA2	ENSP00000276704	ENSP00000333433	chromosome 8 open reading frame 76	spindle and kinetochore associated complex subunit 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubu [...]	0.457
DCAF13	C8orf76	ENSP00000297579	ENSP00000276704	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	chromosome 8 open reading frame 76	0.412
DCAF13	FAM91A1	ENSP00000297579	ENSP00000335082	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	family with sequence similarity 91, member A1	0.433
DCAF13	UBC	ENSP00000297579	ENSP00000344818	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	ubiquitin C	0.912
DEPDC1B	FAM91A1	ENSP00000265036	ENSP00000335082	DEP domain containing 1B	family with sequence similarity 91, member A1	0.450
DEPDC1B	NUDCD1	ENSP00000265036	ENSP00000239690	DEP domain containing 1B	NudC domain containing 1	0.468
FAM91A1	C8orf76	ENSP00000335082	ENSP00000276704	family with sequence similarity 91, member A1	chromosome 8 open reading frame 76	0.565
FAM91A1	DCAF13	ENSP00000335082	ENSP00000297579	family with sequence similarity 91, member A1	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	0.433
FAM91A1	DEPDC1B	ENSP00000335082	ENSP00000265036	family with sequence similarity 91, member A1	DEP domain containing 1B	0.450
FAM91A1	IMPAD1	ENSP00000335082	ENSP00000262644	family with sequence similarity 91, member A1	inositol monophosphatase domain containing 1; May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3’,5’-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation (By similarity)	0.505
FAM91A1	MRPS23	ENSP00000335082	ENSP00000320184	family with sequence similarity 91, member A1	mitochondrial ribosomal protein S23	0.450
FAM91A1	MTL5	ENSP00000335082	ENSP00000255087	family with sequence similarity 91, member A1	metallothionein-like 5, testis-specific (tesmin); May have a role in spermatogenesis (Probable)	0.429
FAM91A1	NUDCD1	ENSP00000335082	ENSP00000239690	family with sequence similarity 91, member A1	NudC domain containing 1	0.416
FAM91A1	SKA2	ENSP00000335082	ENSP00000333433	family with sequence similarity 91, member A1	spindle and kinetochore associated complex subunit 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubu [...]	0.470
FAM91A1	UBC	ENSP00000335082	ENSP00000344818	family with sequence similarity 91, member A1	ubiquitin C	0.795
FAM91A1	WDR67	ENSP00000335082	ENSP00000287380	family with sequence similarity 91, member A1	WD repeat domain 67	0.561
IMPAD1	FAM91A1	ENSP00000262644	ENSP00000335082	inositol monophosphatase domain containing 1; May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3’,5’-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation (By similarity)	family with sequence similarity 91, member A1	0.505

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