node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL4A3BP | STAR | ENSP00000369862 | ENSP00000276449 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | steroidogenic acute regulatory protein; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone | 0.606 |
COL4A3BP | STARD10 | ENSP00000369862 | ENSP00000335247 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | 0.414 |
COL4A3BP | STARD3 | ENSP00000369862 | ENSP00000337446 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | StAR-related lipid transfer (START) domain containing 3; Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain | 0.733 |
COL4A3BP | STARD6 | ENSP00000369862 | ENSP00000310814 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | StAR-related lipid transfer (START) domain containing 6; May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity) | 0.578 |
GRB2 | STARD10 | ENSP00000339007 | ENSP00000335247 | growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | 0.517 |
PI16 | STARD10 | ENSP00000362778 | ENSP00000335247 | peptidase inhibitor 16; Putative serine protease inhibitor (By similarity) | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | 0.529 |
STAR | COL4A3BP | ENSP00000276449 | ENSP00000369862 | steroidogenic acute regulatory protein; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.606 |
STAR | STARD10 | ENSP00000276449 | ENSP00000335247 | steroidogenic acute regulatory protein; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | 0.421 |
STARD10 | COL4A3BP | ENSP00000335247 | ENSP00000369862 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.414 |
STARD10 | GRB2 | ENSP00000335247 | ENSP00000339007 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway | 0.517 |
STARD10 | PI16 | ENSP00000335247 | ENSP00000362778 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | peptidase inhibitor 16; Putative serine protease inhibitor (By similarity) | 0.529 |
STARD10 | STAR | ENSP00000335247 | ENSP00000276449 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | steroidogenic acute regulatory protein; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone | 0.421 |
STARD10 | STARD13 | ENSP00000335247 | ENSP00000338785 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | StAR-related lipid transfer (START) domain containing 13 | 0.464 |
STARD10 | STARD3 | ENSP00000335247 | ENSP00000337446 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | StAR-related lipid transfer (START) domain containing 3; Binds and transports cholesterol. Promotes steroidogenesis in placenta and brain | 0.412 |
STARD10 | STARD6 | ENSP00000335247 | ENSP00000310814 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | StAR-related lipid transfer (START) domain containing 6; May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity) | 0.629 |
STARD10 | STARD8 | ENSP00000335247 | ENSP00000363727 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | StAR-related lipid transfer (START) domain containing 8; Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1 | 0.678 |
STARD10 | STARD9 | ENSP00000335247 | ENSP00000290607 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | StAR-related lipid transfer (START) domain containing 9; Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM) | 0.623 |
STARD10 | TMCO7 | ENSP00000335247 | ENSP00000261778 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | transmembrane and coiled-coil domains 7 | 0.546 |
STARD13 | STARD10 | ENSP00000338785 | ENSP00000335247 | StAR-related lipid transfer (START) domain containing 13 | StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes | 0.464 |
STARD13 | STARD6 | ENSP00000338785 | ENSP00000310814 | StAR-related lipid transfer (START) domain containing 13 | StAR-related lipid transfer (START) domain containing 6; May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity) | 0.533 |