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STRINGSTRING
APIP APIP PPP6R1 PPP6R1 FBXO22 FBXO22 CCDC94 CCDC94 ALDH18A1 ALDH18A1 PTCHD1 PTCHD1 TMLHE TMLHE ALDH9A1 ALDH9A1 PPP6R2 PPP6R2 TRIM21 TRIM21 TADA2A TADA2A
"TMLHE" - trimethyllysine hydroxylase, epsilon in Homo sapiens
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TMLHEtrimethyllysine hydroxylase, epsilon; Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML) (421 aa)    
Predicted Functional Partners:
ALDH18A1
aldehyde dehydrogenase 18 family, member A1 (795 aa)
            score_image   0.644
TADA2A
transcriptional adaptor 2A; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling (443 aa)
            score_image   0.623
PTCHD1
patched domain containing 1 (888 aa)
            score_image   0.605
CCDC94
coiled-coil domain containing 94 (323 aa)
            score_image   0.602
FBXO22
F-box protein 22; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function (403 aa)
            score_image   0.598
ALDH9A1
aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction (518 aa)
      score_image     score_image   0.570
PPP6R2
protein phosphatase 6, regulatory subunit 2; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha (933 aa)
            score_image   0.547
PPP6R1
protein phosphatase 6, regulatory subunit 1; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha (881 aa)
            score_image   0.513
TRIM21
tripartite motif containing 21; E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)- like complex is shown to mediate ubiquitination of CDKN1B (’Thr- 187’ phosphorylated-form), thereby promoting its degradat [...] (475 aa)
            score_image   0.489
APIP
APAF1 interacting protein; Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death (By similarity) (242 aa)
            score_image   0.487
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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