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DEFB1 DEFB1 DEFB107B DEFB107B DEFB103A DEFB103A DEFB106A DEFB106A DEFB105A DEFB105A DEFB108B DEFB108B DEFB107A DEFB107A DEFB104A DEFB104A FAM90A26P FAM90A26P LRLE1 LRLE1
"DEFB106A" - defensin, beta 106A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB106Adefensin, beta 106A; Has antibacterial activity (65 aa)    
Predicted Functional Partners:
DEFB108B
defensin, beta 108B; Has antibacterial activity (By similarity) (73 aa)
            score_image   0.720
DEFB105A
defensin, beta 105A; Has antibacterial activity (Potential) (78 aa)
            score_image   0.645
DEFB1
defensin, beta 1; Has bactericidal activity (By similarity) (68 aa)
            score_image   0.635
DEFB104A
defensin, beta 104A; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103 (72 aa)
            score_image   0.578
DEFB107B
defensin, beta 107B; Has antibacterial activity (Potential) (70 aa)
            score_image   0.459
DEFB107A
defensin, beta 107A; Has antibacterial activity (Potential) (70 aa)
            score_image   0.459
DEFB103A
defensin, beta 103A; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed (67 aa)
            score_image   0.459
LRLE1
Liver-related low express protein 1 (57 aa)
            score_image   0.416
FAM90A26P
family with sequence similarity 90, member A26, pseudogene (464 aa)
            score_image   0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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