ZPBP2 protein (Homo sapiens) - STRING network view

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ZPBP2

zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization (338 aa)

Predicted Functional Partners:

GSDMB

0.813

ORMDL3

0.810

IKZF3

0.750

GRB7

0.680

GSDMA

0.645

GRB10

0.606

EAF2

0.606

TMEM39A

0.565

OR8D4

0.518

PSMD3

0.507

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAF2	GSDMB	ENSP00000273668	ENSP00000353465	ELL associated factor 2; Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo	gasdermin B; May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells	0.608
EAF2	ORMDL3	ENSP00000273668	ENSP00000304858	ELL associated factor 2; Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo	ORM1-like 3 (S. cerevisiae); Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling	0.439
EAF2	ZPBP2	ENSP00000273668	ENSP00000335384	ELL associated factor 2; Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo	zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization	0.606
GRB10	GRB7	ENSP00000381793	ENSP00000403459	growth factor receptor-bound protein 10	growth factor receptor-bound protein 7	0.903
GRB10	ZPBP2	ENSP00000381793	ENSP00000335384	growth factor receptor-bound protein 10	zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization	0.606
GRB7	GRB10	ENSP00000403459	ENSP00000381793	growth factor receptor-bound protein 7	growth factor receptor-bound protein 10	0.903
GRB7	IKZF3	ENSP00000403459	ENSP00000344544	growth factor receptor-bound protein 7	IKAROS family zinc finger 3 (Aiolos)	0.446
GRB7	ZPBP2	ENSP00000403459	ENSP00000335384	growth factor receptor-bound protein 7	zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization	0.680
GSDMA	ORMDL3	ENSP00000301659	ENSP00000304858	gasdermin A; Induces apoptosis	ORM1-like 3 (S. cerevisiae); Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling	0.623
GSDMA	PSMD3	ENSP00000301659	ENSP00000264639	gasdermin A; Induces apoptosis	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins	0.457
GSDMA	ZPBP2	ENSP00000301659	ENSP00000335384	gasdermin A; Induces apoptosis	zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization	0.645
GSDMB	EAF2	ENSP00000353465	ENSP00000273668	gasdermin B; May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells	ELL associated factor 2; Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo	0.608
GSDMB	IKZF3	ENSP00000353465	ENSP00000344544	gasdermin B; May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells	IKAROS family zinc finger 3 (Aiolos)	0.608
GSDMB	ORMDL3	ENSP00000353465	ENSP00000304858	gasdermin B; May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells	ORM1-like 3 (S. cerevisiae); Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling	0.824
GSDMB	PSMD3	ENSP00000353465	ENSP00000264639	gasdermin B; May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins	0.471
GSDMB	ZPBP2	ENSP00000353465	ENSP00000335384	gasdermin B; May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells	zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization	0.813
IKZF3	GRB7	ENSP00000344544	ENSP00000403459	IKAROS family zinc finger 3 (Aiolos)	growth factor receptor-bound protein 7	0.446
IKZF3	GSDMB	ENSP00000344544	ENSP00000353465	IKAROS family zinc finger 3 (Aiolos)	gasdermin B; May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells	0.608
IKZF3	ORMDL3	ENSP00000344544	ENSP00000304858	IKAROS family zinc finger 3 (Aiolos)	ORM1-like 3 (S. cerevisiae); Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling	0.588
IKZF3	ZPBP2	ENSP00000344544	ENSP00000335384	IKAROS family zinc finger 3 (Aiolos)	zona pellucida binding protein 2; May be implicated in gamete interaction during fertilization	0.750

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