Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | SPATA12 | spermatogenesis associated 12 (190 aa) | ||||||||||||
Predicted Functional Partners:
| ||||||||||||||
 | RSBN1 | round spermatid basic protein 1 (802 aa) |
 |
0.581 | ||||||||||
 | TEKT3 | tektin 3; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility (By similarity) (490 aa) |
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0.513 | ||||||||||
 | SPEF1 | sperm flagellar 1 (236 aa) |
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0.509 | ||||||||||
 | SPATA16 | spermatogenesis associated 16 (569 aa) |
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0.503 | ||||||||||
 | RTP4 | receptor (chemosensory) transporter protein 4 (246 aa) |
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0.459 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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