BTBD7 protein (Homo sapiens) - STRING network view

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Score

BTBD7

BTB (POZ) domain containing 7 (1132 aa)

Predicted Functional Partners:

SNAI2

0.942

FAM118B

0.566

SEC24D

0.541

ZNF530

0.533

MITD1

0.528

OR4M1

0.513

CDH1

0.512

TCEAL3

0.501

C3orf33

0.498

LRRC59

0.439

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTBD7	C3orf33	ENSP00000335615	ENSP00000445446	BTB (POZ) domain containing 7	chromosome 3 open reading frame 33	0.498
BTBD7	CDH1	ENSP00000335615	ENSP00000261769	BTB (POZ) domain containing 7	cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7	0.512
BTBD7	FAM118B	ENSP00000335615	ENSP00000433343	BTB (POZ) domain containing 7	family with sequence similarity 118, member B	0.566
BTBD7	LRRC59	ENSP00000335615	ENSP00000225972	BTB (POZ) domain containing 7	leucine rich repeat containing 59; Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores	0.439
BTBD7	MITD1	ENSP00000335615	ENSP00000289359	BTB (POZ) domain containing 7	MIT, microtubule interacting and transport, domain containing 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex	0.528
BTBD7	OR4M1	ENSP00000335615	ENSP00000319654	BTB (POZ) domain containing 7	olfactory receptor, family 4, subfamily M, member 1; Odorant receptor (Potential)	0.513
BTBD7	SEC24D	ENSP00000335615	ENSP00000280551	BTB (POZ) domain containing 7	SEC24 family, member D (S. cerevisiae); Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex	0.541
BTBD7	SNAI2	ENSP00000335615	ENSP00000020945	BTB (POZ) domain containing 7	snail homolog 2 (Drosophila); Transcriptional repressor that modulates both activator- dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1- induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2- box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved [...]	0.942
BTBD7	TCEAL3	ENSP00000335615	ENSP00000243286	BTB (POZ) domain containing 7	transcription elongation factor A (SII)-like 3; May be involved in transcriptional regulation	0.501
BTBD7	ZNF530	ENSP00000335615	ENSP00000332861	BTB (POZ) domain containing 7	zinc finger protein 530; May be involved in transcriptional regulation (By similarity)	0.533
C3orf33	BTBD7	ENSP00000445446	ENSP00000335615	chromosome 3 open reading frame 33	BTB (POZ) domain containing 7	0.498
C3orf33	LRRC59	ENSP00000445446	ENSP00000225972	chromosome 3 open reading frame 33	leucine rich repeat containing 59; Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores	0.457
C3orf33	MITD1	ENSP00000445446	ENSP00000289359	chromosome 3 open reading frame 33	MIT, microtubule interacting and transport, domain containing 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex	0.519
CDH1	BTBD7	ENSP00000261769	ENSP00000335615	cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7	BTB (POZ) domain containing 7	0.512
CDH1	SNAI2	ENSP00000261769	ENSP00000020945	cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7	snail homolog 2 (Drosophila); Transcriptional repressor that modulates both activator- dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1- induced transcriptional repression of the TJ protein, occludin (OCLN) and subsequent oncogenic transformation of epithelial cells (By similarity). Represses BRCA2 expression by binding to its E2- box-containing silencer and recruiting CTBP1 and HDAC1 in breast cells. In epidermal keratinocytes, binds to the E-box in ITGA3 promoter and represses its transcription. Involved [...]	0.998
FAM118B	BTBD7	ENSP00000433343	ENSP00000335615	family with sequence similarity 118, member B	BTB (POZ) domain containing 7	0.566
LRRC59	BTBD7	ENSP00000225972	ENSP00000335615	leucine rich repeat containing 59; Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores	BTB (POZ) domain containing 7	0.439
LRRC59	C3orf33	ENSP00000225972	ENSP00000445446	leucine rich repeat containing 59; Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores	chromosome 3 open reading frame 33	0.457
LRRC59	MITD1	ENSP00000225972	ENSP00000289359	leucine rich repeat containing 59; Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores	MIT, microtubule interacting and transport, domain containing 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex	0.507
MITD1	BTBD7	ENSP00000289359	ENSP00000335615	MIT, microtubule interacting and transport, domain containing 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex	BTB (POZ) domain containing 7	0.528

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