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STRINGSTRING
CSMD1 CSMD1 RNFT2 RNFT2 CSNK2B CSNK2B NTRK1 NTRK1 ENSG00000263020 ENSG00000263020 SLITRK4 SLITRK4 ZNF275 ZNF275 CSMD2 CSMD2 H2AFB3 H2AFB3 CSMD3 CSMD3 FAM81A FAM81A
"SLITRK4" - SLIT and NTRK-like family, member 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLITRK4SLIT and NTRK-like family, member 4; Suppresses neurite outgrowth (By similarity) (837 aa)    
Predicted Functional Partners:
NTRK1
neurotrophic tyrosine kinase, receptor, type 1 (796 aa)
            score_image   0.562
RNFT2
ring finger protein, transmembrane 2 (444 aa)
            score_image   0.484
CSMD1
CUB and Sushi multiple domains 1; Potential suppressor of squamous cell carcinomas (3564 aa)
            score_image   0.465
ENSG00000263020
Lymphocyte antigen 6 complex, locus G5B (228 aa)
            score_image   0.457
CSNK2B
casein kinase 2, beta polypeptide (215 aa)
            score_image   0.457
FAM81A
family with sequence similarity 81, member A (368 aa)
            score_image   0.455
CSMD3
CUB and Sushi multiple domains 3 (3707 aa)
            score_image   0.438
CSMD2
CUB and Sushi multiple domains 2 (3487 aa)
            score_image   0.422
ZNF275
zinc finger protein 275; May be involved in transcriptional regulation (459 aa)
            score_image   0.418
H2AFB3
H2A histone family, member B3; Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and a [...] (115 aa)
            score_image   0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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