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GBGT1 GBGT1 C1GALT1C1 C1GALT1C1 C1GALT1 C1GALT1 EFCAB2 EFCAB2 ST6GALNAC1 ST6GALNAC1 GCNT1 GCNT1 GALNTL1 GALNTL1 B4GALNT4 B4GALNT4 RASGEF1C RASGEF1C PLEKHD1 PLEKHD1 CCDC102A CCDC102A
"GALNTL1" - UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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Predicted Interactions
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fusion edge
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textmining
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protein homology
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GALNTL1UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase-like 1; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor (By similarity) (558 aa)    
Predicted Functional Partners:
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1; Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development (363 aa)
          score_image score_image   0.932
ST6GALNAC1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (600 aa)
          score_image score_image   0.924
C1GALT1C1
C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) (318 aa)
          score_image score_image   0.919
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2; Forms critical branches in O-glycans (428 aa)
          score_image score_image   0.905
CCDC102A
coiled-coil domain containing 102A (550 aa)
            score_image   0.569
PLEKHD1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 (506 aa)
            score_image   0.533
EFCAB2
EF-hand calcium binding domain 2 (162 aa)
            score_image   0.491
RASGEF1C
RasGEF domain family, member 1C; Guanine nucleotide exchange factor (GEF) (By similarity) (466 aa)
            score_image   0.452
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans (1039 aa)
            score_image   0.436
GBGT1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1; Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens (347 aa)
            score_image   0.430
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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