node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PLEKHD1 | SLC39A9 | ENSP00000317175 | ENSP00000336887 | pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 | solute carrier family 39 (zinc transporter), member 9; May act as a zinc-influx transporter (By similarity) | 0.635 |
SLC30A5 | SLC39A10 | ENSP00000379836 | ENSP00000352655 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | solute carrier family 39 (zinc transporter), member 10; May act as a zinc-influx transporter | 0.858 |
SLC30A5 | SLC39A11 | ENSP00000379836 | ENSP00000445829 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity) | 0.703 |
SLC30A5 | SLC39A13 | ENSP00000379836 | ENSP00000354689 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | solute carrier family 39 (zinc transporter), member 13; Acts as a zinc-influx transporter | 0.820 |
SLC30A5 | SLC39A5 | ENSP00000379836 | ENSP00000266980 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | solute carrier family 39 (metal ion transporter), member 5; May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status (By similarity) | 0.890 |
SLC30A5 | SLC39A7 | ENSP00000379836 | ENSP00000363807 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | solute carrier family 39 (zinc transporter), member 7 | 0.812 |
SLC30A5 | SLC39A8 | ENSP00000379836 | ENSP00000349174 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | solute carrier family 39 (zinc transporter), member 8; Acts as a zinc-influx transporter | 0.854 |
SLC30A5 | SLC39A9 | ENSP00000379836 | ENSP00000336887 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | solute carrier family 39 (zinc transporter), member 9; May act as a zinc-influx transporter (By similarity) | 0.770 |
SLC30A7 | SLC39A10 | ENSP00000350278 | ENSP00000352655 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | solute carrier family 39 (zinc transporter), member 10; May act as a zinc-influx transporter | 0.853 |
SLC30A7 | SLC39A11 | ENSP00000350278 | ENSP00000445829 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity) | 0.632 |
SLC30A7 | SLC39A13 | ENSP00000350278 | ENSP00000354689 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | solute carrier family 39 (zinc transporter), member 13; Acts as a zinc-influx transporter | 0.692 |
SLC30A7 | SLC39A5 | ENSP00000350278 | ENSP00000266980 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | solute carrier family 39 (metal ion transporter), member 5; May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status (By similarity) | 0.882 |
SLC30A7 | SLC39A7 | ENSP00000350278 | ENSP00000363807 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | solute carrier family 39 (zinc transporter), member 7 | 0.777 |
SLC30A7 | SLC39A8 | ENSP00000350278 | ENSP00000349174 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | solute carrier family 39 (zinc transporter), member 8; Acts as a zinc-influx transporter | 0.827 |
SLC30A7 | SLC39A9 | ENSP00000350278 | ENSP00000336887 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | solute carrier family 39 (zinc transporter), member 9; May act as a zinc-influx transporter (By similarity) | 0.693 |
SLC39A10 | SLC30A5 | ENSP00000352655 | ENSP00000379836 | solute carrier family 39 (zinc transporter), member 10; May act as a zinc-influx transporter | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | 0.858 |
SLC39A10 | SLC30A7 | ENSP00000352655 | ENSP00000350278 | solute carrier family 39 (zinc transporter), member 10; May act as a zinc-influx transporter | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) | 0.853 |
SLC39A10 | SLC39A11 | ENSP00000352655 | ENSP00000445829 | solute carrier family 39 (zinc transporter), member 10; May act as a zinc-influx transporter | solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity) | 0.654 |
SLC39A10 | SLC39A9 | ENSP00000352655 | ENSP00000336887 | solute carrier family 39 (zinc transporter), member 10; May act as a zinc-influx transporter | solute carrier family 39 (zinc transporter), member 9; May act as a zinc-influx transporter (By similarity) | 0.638 |
SLC39A11 | SLC30A5 | ENSP00000445829 | ENSP00000379836 | solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity) | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP | 0.703 |