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STRINGSTRING
C1orf123 C1orf123 COASY COASY KCTD1 KCTD1 KIAA1958 KIAA1958 STAC STAC ZMYM4 ZMYM4 SOCS3 SOCS3 QRICH1 QRICH1
KIAA1958 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIAA1958KIAA1958 (716 aa)    
Predicted Functional Partners:
ZMYM4
zinc finger, MYM-type 4; Plays a role in the regulation of cell morphology and cytoskeletal organization (1548 aa)
            score_image   0.586
KCTD1
potassium channel tetramerisation domain containing 1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent (865 aa)
            score_image   0.583
C1orf123
chromosome 1 open reading frame 123 (160 aa)
            score_image   0.583
QRICH1
glutamine-rich 1 (776 aa)
            score_image   0.580
SOCS3
suppressor of cytokine signaling 3; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL [...] (225 aa)
        score_image       0.551
STAC
SH3 and cysteine rich domain; Probably involved in a neuron-specific signal transduction (402 aa)
        score_image       0.551
COASY
CoA synthase; Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation (593 aa)
        score_image       0.516
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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