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CRELD2 CRELD2 SMYD4 SMYD4 CLASRP CLASRP SYNJ2 SYNJ2 CLPTM1 CLPTM1 ASXL2 ASXL2 UBC UBC TMEM9B TMEM9B ICT1 ICT1 EHD1 EHD1 EHD3 EHD3
"CLPTM1" - cleft lip and palate associated transmembrane protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CLPTM1cleft lip and palate associated transmembrane protein 1; May play a role in T-cell development (By similarity) (669 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.849
SYNJ2
synaptojanin 2; Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis (1496 aa)
            score_image   0.740
ICT1
immature colon carcinoma transcript 1; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (206 aa)
        score_image       0.644
TMEM9B
TMEM9 domain family, member B (198 aa)
            score_image   0.637
ASXL2
additional sex combs like 2 (Drosophila); Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity). Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome prol [...] (1435 aa)
            score_image   0.607
SMYD4
SET and MYND domain containing 4 (804 aa)
            score_image   0.564
CLASRP
CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity) (674 aa)
            score_image   0.518
EHD1
EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (534 aa)
            score_image   0.513
CRELD2
cysteine-rich with EGF-like domains 2 (402 aa)
            score_image   0.474
EHD3
EH-domain containing 3; Plays a role in endocytic transport (535 aa)
            score_image   0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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