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RRAGC RRAGC RRAGD RRAGD LYSMD1 LYSMD1 NCK2 NCK2 MYADM MYADM SEPT11 SEPT11 NPM1 NPM1 KIT KIT FLRT1 FLRT1 FAM84B FAM84B PLLP PLLP
"MYADM" - myeloid-associated differentiation marker in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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second shell of interactors
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experimentally determined
Predicted Interactions
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Score
MYADMmyeloid-associated differentiation marker (322 aa)    
Predicted Functional Partners:
PLLP
plasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity) (182 aa)
            score_image   0.862
RRAGD
Ras-related GTP binding D; Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids (400 aa)
            score_image   0.614
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinosit [...] (976 aa)
            score_image   0.607
FLRT1
fibronectin leucine rich transmembrane protein 1; May have a function in cell adhesion and/or receptor signaling (674 aa)
            score_image   0.530
FAM84B
family with sequence similarity 84, member B (310 aa)
            score_image   0.528
NCK2
NCK adaptor protein 2; Adapter protein which associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling (380 aa)
            score_image   0.509
RRAGC
Ras-related GTP binding C; Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids (399 aa)
            score_image   0.485
LYSMD1
LysM, putative peptidoglycan-binding, domain containing 1 (227 aa)
            score_image   0.468
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin) (294 aa)
            score_image   0.459
SEPT11
septin 11; Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy (429 aa)
            score_image   0.430
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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