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CHURC1 CHURC1 HDHD1 HDHD1 LANCL3 LANCL3 CCAR1 CCAR1 PLCXD1 PLCXD1 PIH1D3 PIH1D3 P2RY8 P2RY8 KIF13A KIF13A BTAF1 BTAF1 ZCCHC13 ZCCHC13 P2RX4 P2RX4
"PIH1D3" - PIH1 domain containing 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIH1D3PIH1 domain containing 3 (214 aa)    
Predicted Functional Partners:
LANCL3
LanC lantibiotic synthetase component C-like 3 (bacterial) (420 aa)
            score_image   0.700
CCAR1
cell division cycle and apoptosis regulator 1 (1150 aa)
        score_image       0.590
BTAF1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner (1849 aa)
        score_image       0.557
KIF13A
kinesin family member 13A (1805 aa)
        score_image       0.557
HDHD1
haloacid dehalogenase-like hydrolase domain containing 1; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine (251 aa)
      score_image     score_image   0.544
ZCCHC13
zinc finger, CCHC domain containing 13 (166 aa)
            score_image   0.499
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4; Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin (388 aa)
        score_image       0.499
CHURC1
churchill domain containing 1; Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself (140 aa)
            score_image   0.477
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1 (323 aa)
            score_image   0.471
P2RY8
purinergic receptor P2Y, G-protein coupled, 8; Probable receptor for purines coupled to G-proteins (359 aa)
            score_image   0.450
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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