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ARHGAP4 ARHGAP4 RENBP RENBP TMEM187 TMEM187 GPRASP1 GPRASP1 HCFC1 HCFC1 TKTL1 TKTL1 AVPR2 AVPR2 AGT AGT AQP2 AQP2 AVP AVP CLCNKA CLCNKA
"AVPR2" - arginine vasopressin receptor 2 in Homo sapiens
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AVPR2arginine vasopressin receptor 2; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption (371 aa)    
Predicted Functional Partners:
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis (485 aa)
            score_image   0.804
AQP2
aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (271 aa)
            score_image   0.727
AVP
arginine vasopressin; Neurophysin 2 specifically binds vasopressin (164 aa)
            score_image   0.720
ARHGAP4
Rho GTPase activating protein 4; Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells (986 aa)
            score_image   0.700
RENBP
renin binding protein; Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway- although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (427 aa)
            score_image   0.681
GPRASP1
G protein-coupled receptor associated sorting protein 1; May modulate lysosomal sorting and functional down- regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes (1395 aa)
            score_image   0.681
TKTL1
transketolase-like 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (By similarity) (596 aa)
            score_image   0.610
TMEM187
transmembrane protein 187 (261 aa)
            score_image   0.570
HCFC1
host cell factor C1 (VP16-accessory protein); Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 ’Lys-4’ methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional a [...] (2035 aa)
            score_image   0.562
CLCNKA
chloride channel, voltage-sensitive Ka; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms (687 aa)
            score_image   0.518
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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