node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL4A3 | COL4A4 | ENSP00000379823 | ENSP00000379866 | collagen, type IV, alpha 3 (Goodpasture antigen) | collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.929 |
COL4A3 | FNDC3B | ENSP00000379823 | ENSP00000338523 | collagen, type IV, alpha 3 (Goodpasture antigen) | fibronectin type III domain containing 3B | 0.493 |
COL4A3 | UBC | ENSP00000379823 | ENSP00000344818 | collagen, type IV, alpha 3 (Goodpasture antigen) | ubiquitin C | 0.525 |
COL4A4 | COL4A3 | ENSP00000379866 | ENSP00000379823 | collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.929 |
COL4A4 | FNDC3B | ENSP00000379866 | ENSP00000338523 | collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | fibronectin type III domain containing 3B | 0.492 |
FNDC3B | COL4A3 | ENSP00000338523 | ENSP00000379823 | fibronectin type III domain containing 3B | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.493 |
FNDC3B | COL4A4 | ENSP00000338523 | ENSP00000379866 | fibronectin type III domain containing 3B | collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.492 |
FNDC3B | HPD | ENSP00000338523 | ENSP00000289004 | fibronectin type III domain containing 3B | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine | 0.612 |
FNDC3B | LNX1 | ENSP00000338523 | ENSP00000263925 | fibronectin type III domain containing 3B | ligand of numb-protein X 1, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity) | 0.506 |
FNDC3B | MPDZ | ENSP00000338523 | ENSP00000370410 | fibronectin type III domain containing 3B | multiple PDZ domain protein | 0.567 |
FNDC3B | SNCA | ENSP00000338523 | ENSP00000338345 | fibronectin type III domain containing 3B | synuclein, alpha (non A4 component of amyloid precursor); May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation | 0.513 |
FNDC3B | TOX4 | ENSP00000338523 | ENSP00000262709 | fibronectin type III domain containing 3B | TOX high mobility group box family member 4; Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase | 0.543 |
FNDC3B | TRIP13 | ENSP00000338523 | ENSP00000166345 | fibronectin type III domain containing 3B | thyroid hormone receptor interactor 13; Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for [...] | 0.641 |
FNDC3B | UBC | ENSP00000338523 | ENSP00000344818 | fibronectin type III domain containing 3B | ubiquitin C | 0.737 |
FNDC3B | USP54 | ENSP00000338523 | ENSP00000345216 | fibronectin type III domain containing 3B | ubiquitin specific peptidase 54 | 0.566 |
HPD | FNDC3B | ENSP00000289004 | ENSP00000338523 | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine | fibronectin type III domain containing 3B | 0.612 |
HPD | UBC | ENSP00000289004 | ENSP00000344818 | 4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine | ubiquitin C | 0.629 |
LNX1 | FNDC3B | ENSP00000263925 | ENSP00000338523 | ligand of numb-protein X 1, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity) | fibronectin type III domain containing 3B | 0.506 |
LNX1 | UBC | ENSP00000263925 | ENSP00000344818 | ligand of numb-protein X 1, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity) | ubiquitin C | 0.576 |
MPDZ | FNDC3B | ENSP00000370410 | ENSP00000338523 | multiple PDZ domain protein | fibronectin type III domain containing 3B | 0.567 |