node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSG00000263620 | NAPB | ENSP00000464383 | ENSP00000366225 | Uncharacterized protein | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | 0.793 |
ENSG00000263620 | SNAP23 | ENSP00000464383 | ENSP00000249647 | Uncharacterized protein | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | 0.993 |
ENSG00000263620 | SNAP25 | ENSP00000464383 | ENSP00000254976 | Uncharacterized protein | synaptosomal-associated protein, 25kDa | 0.927 |
ENSG00000263620 | STX3 | ENSP00000464383 | ENSP00000338562 | Uncharacterized protein | syntaxin 3; Potentially involved in docking of synaptic vesicles at presynaptic active zones | 0.988 |
ENSG00000263620 | STXBP1 | ENSP00000464383 | ENSP00000362399 | Uncharacterized protein | syntaxin binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1-1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions | 0.984 |
ENSG00000263620 | STXBP2 | ENSP00000464383 | ENSP00000221283 | Uncharacterized protein | syntaxin binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N- ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells | 0.881 |
NAPB | ENSG00000263620 | ENSP00000366225 | ENSP00000464383 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | Uncharacterized protein | 0.793 |
NAPB | SNAP23 | ENSP00000366225 | ENSP00000249647 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | 0.878 |
NAPB | SNAP25 | ENSP00000366225 | ENSP00000254976 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | synaptosomal-associated protein, 25kDa | 0.546 |
NAPB | STX3 | ENSP00000366225 | ENSP00000338562 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | syntaxin 3; Potentially involved in docking of synaptic vesicles at presynaptic active zones | 0.980 |
NAPB | STXBP1 | ENSP00000366225 | ENSP00000362399 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | syntaxin binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1-1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions | 0.654 |
NAPB | STXBP2 | ENSP00000366225 | ENSP00000221283 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | syntaxin binding protein 2; Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N- ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells | 0.654 |
NAPB | VAMP1 | ENSP00000366225 | ENSP00000379602 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | vesicle-associated membrane protein 1 (synaptobrevin 1); Involved in the targeting and/or fusion of transport vesicles to their target membrane | 0.806 |
NAPB | VAMP2 | ENSP00000366225 | ENSP00000314214 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusion of transport vesicles to their target membrane | 0.861 |
NAPB | VAMP3 | ENSP00000366225 | ENSP00000054666 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | vesicle-associated membrane protein 3; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network | 0.861 |
NAPB | VAMP8 | ENSP00000366225 | ENSP00000263864 | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | vesicle-associated membrane protein 8; SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also required for dense-granule secretion in platelets. Plays also a role in regulated enzyme secretion in pancreatic acinar cells [...] | 0.869 |
SNAP23 | ENSG00000263620 | ENSP00000249647 | ENSP00000464383 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | Uncharacterized protein | 0.993 |
SNAP23 | NAPB | ENSP00000249647 | ENSP00000366225 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) | 0.878 |
SNAP23 | STX3 | ENSP00000249647 | ENSP00000338562 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin 3; Potentially involved in docking of synaptic vesicles at presynaptic active zones | 0.999 |
SNAP23 | STXBP1 | ENSP00000249647 | ENSP00000362399 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion | syntaxin binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1-1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions | 0.885 |