Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
GPX8 GPX8 FAM57A FAM57A GPX7 GPX7 GPX1 GPX1 GGT7 GGT7 GSS GSS GPX3 GPX3 GPX2 GPX2 GCLC GCLC GPX6 GPX6 GPX4 GPX4
"GGT7" - gamma-glutamyltransferase 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GGT7gamma-glutamyltransferase 7; Cleaves glutathione conjugates (By similarity) (662 aa)    
Predicted Functional Partners:
FAM57A
family with sequence similarity 57, member A (257 aa)
        score_image   score_image   0.989
GSS
glutathione synthetase (474 aa)
          score_image score_image   0.974
GPX2
glutathione peroxidase 2 (gastrointestinal); Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors (190 aa)
          score_image score_image   0.925
GCLC
glutamate-cysteine ligase, catalytic subunit (637 aa)
          score_image score_image   0.924
GPX7
glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks (187 aa)
          score_image score_image   0.923
GPX4
glutathione peroxidase 4; Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity) (197 aa)
          score_image score_image   0.919
GPX3
glutathione peroxidase 3 (plasma); Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione (226 aa)
          score_image score_image   0.917
GPX1
glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown (203 aa)
          score_image score_image   0.916
GPX8
glutathione peroxidase 8 (putative) (209 aa)
          score_image score_image   0.915
GPX6
glutathione peroxidase 6 (olfactory) (221 aa)
          score_image score_image   0.915
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (30%)